Results 41 to 50 of about 28,531 (210)

Early removal of senescent cells protects retinal ganglion cells loss in experimental ocular hypertension. [PDF]

open access: yes, 2020
Experimental ocular hypertension induces senescence of retinal ganglion cells (RGCs) that mimics events occurring in human glaucoma. Senescence-related chromatin remodeling leads to profound transcriptional changes including the upregulation of a subset ...
Jabari, Mary   +7 more
core  

The natural dietary genistein boosts bacteriophage-mediated cancer cell killing by improving phage-targeted tumor cell transduction [PDF]

open access: yes, 2016
Gene therapy has long been regarded as a promising treatment for cancer. However, cancer gene therapy is still facing the challenge of targeting gene delivery vectors specifically to tumors when administered via clinically acceptable non-invasive ...
Albahrani, M   +5 more
core   +2 more sources

Functional principal components analysis via penalized rank one approximation [PDF]

open access: yes, 2008
Two existing approaches to functional principal components analysis (FPCA) are due to Rice and Silverman (1991) and Silverman (1996), both based on maximizing variance but introducing penalization in different ways.
Buja, Andreas   +2 more
core   +5 more sources

Fast stable direct fitting and smoothness selection for Generalized Additive Models [PDF]

open access: yes, 2007
Existing computationally efficient methods for penalized likelihood GAM fitting employ iterative smoothness selection on working linear models (or working mixed models).
Akaike H.   +25 more
core   +3 more sources

GCV for Tikhonov regularization via global Golub–Kahan decomposition

open access: yesNumerical Linear Algebra with Applications, 2016
SummaryGeneralized cross validation is a popular approach to determining the regularization parameter in Tikhonov regularization. The regularization parameter is chosen by minimizing an expression, which is easy to evaluate for small‐scale problems, but prohibitively expensive to compute for large‐scale ones.
FENU, CATERINA   +2 more
openaire   +4 more sources

Exploring genetic variability and association in QPM maize (Zea mays) inbred lines

open access: yesElectronic Journal of Plant Breeding, 2023
Variability and association studies help to assess the variation among the genotypes and interactions between grain yield and its component traits for enhancing the usefulness of selection.
Anvesh Ellandula1 , Ajay Kumar*1 , Satish Kumar Singh2 , Asish Narayan3 , Uttej Karla4 and U.S. Sree Vathsa Sagar5
doaj   +1 more source

Automatic estimation of the regularization parameter in 2-D focusing gravity inversion: an application to the Safo manganese mine in northwest of Iran

open access: yes, 2014
We investigate the use of Tikhonov regularization with the minimum support stabilizer for underdetermined 2-D inversion of gravity data. This stabilizer produces models with non-smooth properties which is useful for identifying geologic structures with ...
Ardestani, Vahid E   +2 more
core   +1 more source

Genetic variability studies on rice (Oryza sativa L.) mutants for yield and yield components in normal and saline stress soil

open access: yesElectronic Journal of Plant Breeding, 2016
The present study was carried out to assess the genetic variability, heritability, genetic advance for yield and yield component characters in four hundred mutant lines of Rice. The crop was raised during kharif 2013 at Agricultural Research Station (ARS)
K. Mahantashivayogayya   +4 more
doaj   +1 more source

Evaluation on genetic variability and trait association in naturally coloured cotton (Gossypium hirsutum L.)

open access: yesElectronic Journal of Plant Breeding, 2023
A study was carried out to understand the genetic variability and trait association in a set of 30 naturally coloured cotton hybrids along with their parents (five colour cotton and six white cotton parents).
R.P. Santhosh Jeyaraj1 , P. Anantharaju2 , A. Subramanian3* , S. Somasundaram2 , N. Chitra3 and N. Premalatha3
doaj   +1 more source

From food security to economic diversification: Heterogeneity of rationales around a rice inventory credit in Madagascar [PDF]

open access: yes, 2009
Le réseau des Caisses d'épargne et de crédit agricole mutuels de Madagascar (CECAM) propose à ses sociétaires un produit innovant de crédit stockage pour le riz depuis 1993.
Bouquet, Emmanuelle   +2 more
core  

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