Results 51 to 60 of about 8,557 (189)
Integrative Zoology, EarlyView.Our analysis revealed that while climate strongly influenced species distributions, habitat change drove most observed delays in distribution responses. In terms of community ecology, dispersed communities exhibited shorter time lags than concentrated groups. Analyses of lag duration revealed a 5–6‐year distribution lag effect in high‐altitude ungulate
Lu Wang +6 more
wiley +1 more source
Molecules, 2021 In the area of gene-directed enzyme prodrug therapy (GDEPT), using herpes simplex virus thymidine kinase (HSV-tk) paired with prodrug ganciclovir (GCV) for cancer treatment has been extensively studied. It is a process involved with two steps whereby the
Alicia J. Sawdon +4 more
doaj +1 more source
Annals of Public and Cooperative Economics, EarlyView.Abstract Traditional bankruptcy literature has primarily focused on commercial enterprises, often overlooking the unique dynamics of cooperatives and other small organizations. This study addresses this g ap by developing a predictive model for insolvency risk within Brazil's supplementary health sector, encompassing both for‐profit and not‐for‐profit ...
Thiago de Oliveira Victorino +2 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.In this large multicentre Spanish inception cohort, biologics/JAK inhibitors were frequently used during the first 5 years after inflammatory bowel disease diagnosis and were associated with reduced hospitalisation risk, although not with lower abdominal surgery rates.
Ana Garre +308 more
wiley +1 more source
The Annals of Statistics, 1998 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
GCV for Tikhonov regularization via global Golub–Kahan decomposition
Numerical Linear Algebra with Applications, 2016 SummaryGeneralized cross validation is a popular approach to determining the regularization parameter in Tikhonov regularization. The regularization parameter is chosen by minimizing an expression, which is easy to evaluate for small‐scale problems, but prohibitively expensive to compute for large‐scale ones.
FENU, CATERINA +2 more
openaire +5 more sources
Dental Traumatology, EarlyView.ABSTRACT Background/Aim Premature loss of primary maxillary incisors after traumatic dental injuries may require secondary rehabilitation in preschool children. Evidence on complications associated with fixed anterior prostheses in this context remains limited.
Alberto Adanero Velasco +3 more
wiley +1 more source
Hepatoma-Targeted Radionuclide Immune Albumin Nanospheres: 131I-antiAFPMcAb-GCV-BSA-NPs
Analytical Cellular Pathology, 2016 An effective strategy has been developed for synthesis of radionuclide immune albumin nanospheres (131I-antiAFPMcAb-GCV-BSA-NPs). In vitro as well as in vivo targeting of 131I-antiAFPMcAb-GCV-BSA-NPs to AFP-positive hepatoma was examined.
Mei Lin +8 more
doaj +1 more source
Transgenic selection and underlying mechanisms in apicomplexan parasites
The FEBS Journal, EarlyView.Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju +2 more
wiley +1 more source
Journal of Ophthalmology, 2019 Purpose. To evaluate the safety and pharmacokinetic changes of ganciclovir (GCV) intraocular injection. Methods. GCV (2 mg/0.1 mL) was injected into rabbit eyes. Aqueous GCV concentration was detected by high-performance liquid chromatography.
Bin-jia Sun +3 more
doaj +1 more source