Results 21 to 30 of about 8,324 (180)

Gene conversion-like events in the diversification of human rearranged IGHV3-23*01 gene sequences

Frontiers in Immunology, 2012
Gene conversion (GCV) as a mechanism of immunoglobulin diversification is well established in a few species. However, definitive evidence of GCV-like events in human immunoglobulin genes is scarce. GCV is mediated by activation-induced cytidine deaminase
Bhargavi eDuvvuri, Gillian E Wu
doaj   +1 more source

Late emergence of A594V and L595W mutations related to ganciclovir resistance in a patient with HCMV retinitis and long-term HIV progression [PDF]

Brazilian Journal of Medical and Biological Research, 2015
The emergence of ganciclovir (GCV) resistance during the treatment of human cytomegalovirus (HCMV) infection is a serious clinical challenge, and is associated with high morbidity and mortality.
S.N. Slavov, F.C. Vilar, V.M.D. Wagatsuma, R.C. Santana, A.A. Machado, B.A.L. da Fonseca, S. Kashima, D.T. Covas   +7 more
doaj   +4 more sources

3p14 De Novo Interstitial Microdeletion in a Patient with Intellectual Disability and Autistic Features with Language Impairment: A Comparison with Similar Cases

Case Reports in Genetics, 2015
To date, few cases of 3p proximal interstitial deletions have been reported and the phenotype and genotype correlation is not well understood. Here, we report a new case of a 3p proximal interstitial deletion.
Ana Belén de la Hoz, Hiart Maortua, Ainhoa García-Rives, María Jesús Martínez-González, Maitane Ezquerra, María-Isabel Tejada   +5 more
doaj   +1 more source

Gross heating value of various shade-trees wood in coffee plantation in Costa Rica and its relation with extractives and specific gravity

Coffee and Cocoa Research Journal, 2018
Shade-trees with energy use in coffee plantations are an important alternative to increase profitability in groforestry systems. The aim of this study was to investigate gross calorific value (GCV) of 15 shade-tree species in coffee plantations in Costa ...
Roger Moya, Róger Bonilla, Carlos Zelada Fonseca   +2 more
doaj   +1 more source

Characterization of pumpkin (Cucurbita moschata Duch. Ex. Poir.) germplasm through genetic variability, heritability and genetic advance

Electronic Journal of Plant Breeding, 2021
Twenty five pumpkin germplasm from the north eastern region were evaluated for twenty traits for the genetic variability, heritability and genetic advance.
MD. Ramjan
doaj   +1 more source

Polymeric Nanovectors Incorporated with Ganciclovir and HSV-tk Encoding Plasmid for Gene-Directed Enzyme Prodrug Therapy

Molecules, 2021
In the area of gene-directed enzyme prodrug therapy (GDEPT), using herpes simplex virus thymidine kinase (HSV-tk) paired with prodrug ganciclovir (GCV) for cancer treatment has been extensively studied. It is a process involved with two steps whereby the
Alicia J. Sawdon, Jun Zhang, Sarah Peng, Esmael M. Alyami, Ching-An Peng   +4 more
doaj   +1 more source

Renal maturation and catch-up clearance of ganciclovir in a preterm neonate: Bayesian pharmacokinetic analysis using a population model. [PDF]

J Pharm Health Care Sci
Background Congenital cytomegalovirus (CMV) infection is a major cause of neonatal morbidity. However, optimizing ganciclovir (GCV) dosing in preterm infants is complicated by immature renal function and developmental pharmacokinetics.
Kata K, Inomata S, Nishikawa M, Ide H, Nakamura K, Yoshida T, Taguchi M.   +6 more
europepmc   +2 more sources

Genetic variability studies for yield and yield components in kodo millet (Paspalum scrobiculatum L.)

Electronic Journal of Plant Breeding, 2017
The experimental material comprised of one hundred and three germplasm accessions of kodo millet (Paspalum scrobiculatum L.) were evaluated to assess the genetic variability, heritability and genetic advance for fifteen yield component traits.
V. Nirubana, K. Ganesamurthy, R. Ravikesavan and, T. Chitdeshwari   +3 more
doaj   +1 more source

Genetic variability studies in ADT 43/Seeraga samba cross derivatives of rice (Oryza sativa L.)

Electronic Journal of Plant Breeding, 2018
In the present investigation 11 quantitative characters viz., days to 50% flowering, plant height, flag leaf length, flag leaf width, leaf length, leaf width, number productive tillers, panicle length, number of filled grain, thousand grain weight ...
M. S. Bharath, M. Madhan Mohan, C. Vanniarajan, V. Veranan Arun Gridhari and, N. Senthil   +4 more
doaj   +1 more source

Genetic variability studies for horticultural traits in muskmelon (Cucumis melo L.)

Electronic Journal of Plant Breeding, 2021
Genetic variability parameters were estimated for yield and yield attributing traits in twenty five genotypes of muskmelon during kharif, 2017 at College of Horticulture, Anantharajupeta, Andhra Pradesh in randomized block design with three ...
G. Indraja*1, Sadarunnisa Syed1, C. Madhumathi2, B. Thanuja Priya2 and M. Reddi Sekhar3
doaj   +1 more source