Results 11 to 20 of about 28,531 (210)

Gene Therapy with HSV1-sr39TK/GCV Exhibits a Stronger Therapeutic Efficacy Than HSV1-TK/GCV in Rat C6 Glioma Cells [PDF]

The Scientific World Journal, 2013
Although the combination of herpes simplex virus type 1 (HSV-1) thymidine kinase (TK) with ganciclovir (GCV) has been shown as a promising suicide gene treatment strategy for glioma, the almost immunodepressive dose of GCV required for its adequate in ...
Lei-qing Li, Fang Shen, Xiao-yan Xu, Hong Zhang, Xiao-feng Yang, Wei-guo Liu   +5 more
doaj   +3 more sources

Hepatoma-Targeted Radionuclide Immune Albumin Nanospheres: 131I-antiAFPMcAb-GCV-BSA-NPs [PDF]

Analytical Cellular Pathology, 2016
An effective strategy has been developed for synthesis of radionuclide immune albumin nanospheres (131I-antiAFPMcAb-GCV-BSA-NPs). In vitro as well as in vivo targeting of 131I-antiAFPMcAb-GCV-BSA-NPs to AFP-positive hepatoma was examined.
Mei Lin, Junxing Huang, Dongsheng Zhang, Xingmao Jiang, Jia Zhang, Hong Yu, Yanhong Xiao, Yujuan Shi, Ting Guo   +8 more
doaj   +3 more sources

Input Layer Regularization and Automated Regularization Hyperparameter Tuning for Myelin Water Estimation Using Deep Learning. [PDF]

NMR Biomed
We propose a novel deep learning algorithm for predicting the myelin water fraction from multiple gradient‐echo or spin‐echo pulse sequences arising in magnetic resonance relaxometry (MRR) measurements of the human brain. Our method incorporates both regularized nonlinear least squares and pure deep learning through a concatenation paradigm known as ...
Modi M, Sule S, Palumbo J, Rozowski M, Hampton GS, Bouhrara M, Czaja W, Spencer RG.   +7 more
europepmc   +2 more sources

Performance of Robust GCV and Modified GCV for Spline Smoothing [PDF]

Scandinavian Journal of Statistics, 2011
Abstract.  While it is a popular selection criterion for spline smoothing, generalized cross‐validation (GCV) occasionally yields severely undersmoothed estimates. Two extensions of GCV called robust GCV (RGCV) and modified GCV have been proposed as more stable criteria. Each involves a parameter that must be chosen, but the only guidance has come from
Lukas, M.A., de Hoog, F.R., Anderssen, R.S.   +2 more
openaire   +2 more sources

Practical use of robust GCV and modified GCV for spline smoothing [PDF]

Computational Statistics, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lukas, M.A., de Hoog, F.R., Anderssen, R.S.   +2 more
openaire   +1 more source

GCVS problems with flare stars [PDF]

International Astronomical Union Colloquium, 1995
The astrometric aspect of cataloguing variable stars becomes more and more important. During the past thirty years there has been approximately an three-fold increase of the number of known variables; now the rate of new discoveries becomes extremely high, and we may expect a new twofold increase in a couple of years due to discoveries made with space ...
Elena V. Kazarovets, Nikolai N. Samus
openaire   +1 more source

Quantitative Real-Time MRI for the Assessment of Gastric Motility. [PDF]

J Magn Reson Imaging
ABSTRACT Background Current reference standards for measuring gastric emptying and motility are not considered optimal due to the time required, ionizing radiation, invasiveness, and spatial resolution. Purpose To assess gastric motility using novel real‐time dynamic magnetic resonance imaging in combination with static measurements for gastric ...
Neubauer L, Forstreuter L, Winter F, Mankertz F, Wielpütz MO, Grajecki DS, Steveling A, Aghdassi AA, Zeißig S, Blackledge MD, Voit D, Frahm J, Schnell S, Weitschies W, Großmann L.   +14 more
europepmc   +2 more sources

Gene conversion-like events in the diversification of human rearranged IGHV3-23*01 gene sequences

Frontiers in Immunology, 2012
Gene conversion (GCV) as a mechanism of immunoglobulin diversification is well established in a few species. However, definitive evidence of GCV-like events in human immunoglobulin genes is scarce. GCV is mediated by activation-induced cytidine deaminase
Bhargavi eDuvvuri, Gillian E Wu
doaj   +1 more source

Comparison modeling of the number population who have been vaccined in East Java using the biresponse Fourier series estimator method with the trend function

Journal Focus Action of Research Mathematic, 2023
Vaksinasi adalah proses pemberian vaksin pada tubuh manusia yang bertujuan untuk meningkatkan kekebalan tubuh secara aktif terhadap suatu penyakit dan tidak menjadi sumber penularan penyakit tersebut.
Ira Yudistira, Naylur Rohman, M Fariz Fadillah Mardianto, Kuzairi   +3 more
doaj   +1 more source

Genetic analysis of polygenic traits in maize

Electronic Journal of Plant Breeding, 2023
Maize is one of the important cereals in the world. It is a good source of carbohydrates (70-87%) and protein (6-13%). To develop a high-yielding variety of any crop, heritability and genetic advance are important selection parameters for the ...
Rajan Prasad Mishra1*, Sandeep Kumar1 , Ashok Kumar2 and Tarkeshwar3
doaj   +1 more source