Results 81 to 90 of about 7,593,248 (327)
GemTools: A fast and efficient approach to estimating genetic ancestry [PDF]
arXiv, 2011 To uncover the genetic basis of complex disease, individuals are often measured at a large number of genetic variants (usually SNPs) across the genome. GemTools provides computationally efficient tools for modeling genetic ancestry based on SNP genotypes.
arxiv
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Genetic Algorithms as Optimalisation Procedures
Theory, Methodology, Practice, 2007 Drawing a parallel between biological and economic evolution provides an opportunity for the description of dynamic economic processes changing in time by using genetic algorithms.
Sándor Karajz
doaj
Heuristic algorithms in topological design of telecommunication networks
Journal of Telecommunications and Information Technology, 2003 The paper addresses the generic topological network design problem and considers the use of various heuristic algorithms for solving the problem. The target of the optimisation is to determine a network structure and demand allocation pattern that would
Piotr Karaś
doaj +1 more source
GA: A Package for Genetic Algorithms in R
, 2013 Genetic algorithms (GAs) are stochastic search algorithms inspired by the basic principles of biological evolution and natural selection. GAs simulate the evolution of living organisms, where the fittest individuals dominate over the weaker ones, by ...
Luca Scrucca
semanticscholar +1 more source
ResistanceGA: An R package for the optimization of resistance surfaces using genetic algorithms
bioRxiv, 2014 Understanding how landscape features affect functional connectivity among populations is a cornerstone of landscape genetic analyses. However, parameterization of resistance surfaces that best describe connectivity is largely a subjective process that ...
W. Peterman
semanticscholar +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source
GENETIC ALGORITHMS OF WORK DISTRIBUTION
Advanced Engineering Research, 2011 The tasks of heterogeneous work distribution among heterogeneous executors taking into account operation and switching process costs are investigated. Genetic algorithms of work distribution that can be used for solving various practical tasks both in ...
Andrey R. Aidinyan, Olga L. Tsvetkova
doaj
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
New Microbes and New Infections, EarlyView., 2014 Abstract We describe a case of fungal keratitis due to Beauveria bassiana in a farmer with Fuchs' dystrophy, treated with amphotericin B. Surgery with penetrating keratoplasty was necessary to resolve the lesions. Susceptibility testing and molecular sequencing permitted the identification and treatment of this rare aetiological agent of invasive ...
M. Ligozzi +8 more
wiley +1 more source