Results 71 to 80 of about 705,563 (279)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

EXPRESS METHOD OF BARCODE GENERATION FROM FACIAL IMAGES [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2014
In the paper a method of generating of standard type linear barcodes from facial images is proposed. The method is based on use of the histogram of facial image brightness, averaging the histogram on a limited number of intervals, quantization of results
G. A. Kukharev   +2 more
doaj  

Chemometrics: From classical to genetic algorithms

open access: yesGrasas y Aceites, 2002
In this paper the fundamentals of Chemometrics are presented, by means of a quick overview of the most relevant techniques for data display, classification, modeling and calibration.
Riccardo Leardi
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

APPLICATION OF THE DIRECTED MUTATION TO CELLULAR AUTOMATA GENERATION PROCESS [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2014
Cellular automata are widely used for the simulation of discrete systems. However, in most cases creation of controlling cellular automata is done manually, empirically or by exhaustive search. A number of papers describe methods for automatic generation
A. V. Tikhomirov, A. A. Shalyto
doaj  

Mining Frequent Itemsets Using Genetic Algorithm

open access: yes, 2010
In general frequent itemsets are generated from large data sets by applying association rule mining algorithms like Apriori, Partition, Pincer-Search, Incremental, Border algorithm etc., which take too much computer time to compute all the frequent ...
Biswas, Sushanta   +3 more
core   +2 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Co-evolutionary Genetic Algorithms for Reactive Scheduling

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
Previous researches provided a reactive scheduling method using a genetic algorithm to improve disturbed production schedules, due to unexpected disruptions, such as delays of manufacturing operations.
Yoshitaka TANIMIZU   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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