Results 81 to 90 of about 3,657,954 (286)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Bio‐Inspired Optimisation Methods Applied to Low Carbon Power and Energy Problems: A Survey
CAAI Transactions on Intelligence TechnologyBio‐inspired optimisation methods have been widely applied to complex real‐world problems, particularly in low‐carbon power and energy systems, where optimisation tasks often involve high‐dimensional, constrained and mixed‐integer characteristics ...
Tianyu Hu +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
A coarse-grained parallelization of genetic algorithms
IJAIN (International Journal of Advances in Intelligent Informatics), 2018 Genetic algorithms are frequently used to solve optimization problems. However, the problems become increasingly complex and time consuming. One solution to speed up the genetic algorithm processing is to use parallelization. The proposed parallelization
Muhamad Radzi Rathomi, Reza Pulungan
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A Genetic Algorithm for the Maximum 2–Packing Set Problem
International Journal of Applied Mathematics and Computer Science, 2020 Given an undirected connected graph G = (V, E), a subset of vertices S is a maximum 2-packing set if the number of edges in the shortest path between any pair of vertices in S is at least 3 and S has the maximum cardinality.
Trejo-Sánchez Joel Antonio +2 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Heuristic algorithms in topological design of telecommunication networks
Journal of Telecommunications and Information Technology, 2003 The paper addresses the generic topological network design problem and considers the use of various heuristic algorithms for solving the problem. The target of the optimisation is to determine a network structure and demand allocation pattern that would
Piotr Karaś
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