Results 141 to 150 of about 4,976,171 (334)

Assessing the efficacy of target adaptive sampling long-read sequencing through hereditary cancer patient genomes

npj Genomic Medicine
Innovations in sequencing technology have led to the discovery of novel mutations that cause inherited diseases. However, many patients with suspected genetic diseases remain undiagnosed.
Wataru Nakamura, Makoto Hirata, Satoyo Oda, Kenichi Chiba, Ai Okada, Raúl Nicolás Mateos, Masahiro Sugawa, Naoko Iida, Mineko Ushiama, Noriko Tanabe, Hiromi Sakamoto, Shigeki Sekine, Akira Hirasawa, Yosuke Kawai, Katsushi Tokunaga, NCBN Controls WGS Consortium, Shin-ichi Tsujimoto, Norio Shiba, Shuichi Ito, Teruhiko Yoshida, Yuichi Shiraishi   +20 more
doaj   +1 more source

A Systematic Literature Review of Mitochondrial DNA Analysis for Horse Genetic Diversity

Animals
This Systematic Literature Review (SLR) consolidates current research on mitochondrial DNA (mtDNA) analysis in horses, focusing on genetic variation, maternal lineage tracing, and haplogroup identification.
Ayman Agbani, Oumaima Aminou, Mohamed Machmoum, Agnes Germot, Bouabid Badaoui, Daniel Petit, Mohammed Piro   +6 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Genetic analysis of duck circovirus in Pekin ducks from South Korea

, 2013
Se-Yeoun Cha, Min Kang, J.-G. Cho, Hyung‐Kwan Jang   +3 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Author Correction: A new SNP genotyping technology Target SNP-seq and its application in genetic analysis of cucumber varieties [PDF]

, 2021
Jian Zhang, Jianjun Yang, Like Zhang, Jiang Luo, Hong Zhao, Jianan Zhang, Changlong Wen   +6 more
openalex   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Assessment of Genetic Diversity in Alfalfa Using DNA Polymorphism Analysis and Statistical Tools [PDF]

C. Petolescu, Ioan Sărac, S. Popescu, Alina-Maria Țenche-Constantinescu, I. Petrescu, D. Camen, A. Turc, G. Fora, Violeta Turcuș, Nicolae Marinel HORABLAGA, Gabriela Gorinoiu, Mariana Ganea, Emilian Onișan   +12 more
openalex   +1 more source

Additional file 5 of Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes

, 2022
Barthélémy Caron, Étienne Patin, Maxime Rotival, Bruno Charbit, Matthew L. Albert, Lluís Quintana‐Murci, Darragh Duffy, Antonio Rausell   +7 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source