Results 161 to 170 of about 27,209,632 (266)

Software and Methods for Analyzing Molecular Genetic Marker Data

, 2003
Genetic analysis of molecular markers has allowed biologists to ask a wide variety of questions. This dissertation explores some aspects of the statistical and computational issues used in the genetic marker data analysis. Chapter 1 gives an introduction
Liu, Kejun
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Systematic genetic analysis of GSDMD, GSDME, and MLKL in PANoptosis. [PDF]

J Biol Chem
Indari O, Giri P, Tweedell RE, Kanneganti TD.   +3 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Clinical characteristics and genetic analysis of different Dandy-Walker malformation. [PDF]

BMC Pregnancy Childbirth
Wei X, Huo P, Shi X, Zhang P, Zhang N, Sun Y.   +5 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Associations of Depression and Antidepressant Use with the Risk of Tuberculosis Sequelae: Insight from Genetic Analysis. [PDF]

Genes (Basel)
Chen T, Ge L, Zhang D, Zhang Y, Zhang H, Wang Y.   +5 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Long-Term Multisystem Comorbidity Patterns in Acute Pancreatitis: Insights From Observational and Genetic Analysis. [PDF]

United European Gastroenterol J
Che T, Fu T, Zhu Y, Ruan X, Sun Y, Geng J, Dan L, Wang X, Zhou C, Zou D, Arsenault BJ, Yuan S, Li X, Wang Z, Zhang X, Chen J, Zhang Y.   +16 more
europepmc   +1 more source

Morphological and genetic analysis of freshwater sponges in Serbia

, 2019
Sponges in Serbian rivers and lakes have not been extensively studied. Hence, the aim of this work was to undertake an investigation of the distribution and phylogenetics of sponge species in Serbian waterbodies. A total of 83 localities on 17 rivers and
Marjanović, Ana, Nikolić, Vera, Nikolić, Nađa, Branković, Marija, Tubić, Bojana, Paunović, Momir, Anđus, Stefan, Đuknić, Jelena   +7 more
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