Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Microsatellite-Based Genetic Analysis of a Wild Alpine Bumblebee and the Environmental Drivers of Its Genetic Diversity. [PDF]
Ecol EvolZhang R, Sun G, Liang C, Liu D, Yan J.
europepmc +1 more source
Quantitative genetic analysis of attractiveness of yeast products to Drosophila [PDF]
Weiru Yan +6 more
openalex +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Cytometric and genetic analysis of Slovenian local apple genotypes. [PDF]
BMC Plant BiolGostinčar K +3 more
europepmc +1 more source
Genetic variability analysis in sugarcane (Saccharum spp. complex) through mutagenesis [PDF]
, 2018 Chaudhari Sd +3 more
openalex
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Genetic analysis of the NifM dependence of the nitrogenase iron proteins. [PDF]
mBioXie Z +6 more
europepmc +1 more source
Correction: Corrigendum: Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy [PDF]
, 2017 F. David Carmona +99 more
openalex +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source