Results 221 to 230 of about 8,691,632 (395)

The Generalized Higher Criticism for Testing SNP-Set Effects in Genetic Association Studies

Journal of the American Statistical Association, 2017
I. Barnett, R. Mukherjee, Xihong Lin
semanticscholar   +1 more source

Association betweenN-acetyltransferase 2 (NAT2) genetic polymorphism and development of breast cancer in post-menopausal Chinese women in Taiwan, an area of great increase in breast cancer incidence [PDF]

, 1999
Chiun‐Sheng Huang, Herng‐Der Chern, Chen‐Yang Shen, Su-Ming Hsu, King‐Jen Chang   +4 more
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

The phenotypic and genetic association between endometriosis and immunological diseases. [PDF]

Hum Reprod
Shigesi N, Harris HR, Fang H, Ndungu A, Lincoln MR, International Endometriosis Genome Consortium, 23andMe Research Team, Cotsapas C, Knight J, Missmer SA, Morris AP, Becker CM, Rahmioglu N, Zondervan KT.   +13 more
europepmc   +1 more source

Geographic cohesiveness versus associations with habitat: genetic subdivision of Bembicium vittatum Philippi (Gastropoda: Littorinidae) in the Houtman Abrolhos Islands [PDF]

, 1996
Michael S. Johnson, Robert Black
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Genetic associations with IBM [PDF]

Nature Reviews Rheumatology, 2017
openaire   +3 more sources

Genetic and Phenotypic Association Between Skin Tearing and Skin Collagen, Protein, and Fat in Broilers

, 1993
A. Cahaner, Michal Gutman, Mark Pines
openalex   +1 more source

Using case‐control designs for genome‐wide screening for associations between genetic markers and disease susceptibility loci [PDF]

, 1999
Quanhe Yang, Muin J. Khoury, Michael Atkinson, Fengzhu Sun, Rong Cheng, W. Dana Flanders   +5 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source