Results 231 to 240 of about 7,627,088 (344)
Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman +17 morewiley +1 more sourceThe phenotypic and genetic association between endometriosis and immunological diseases. [PDF]
Hum ReprodShigesi N, Harris HR, Fang H, Ndungu A, Lincoln MR, International Endometriosis Genome Consortium, 23andMe Research Team, Cotsapas C, Knight J, Missmer SA, Morris AP, Becker CM, Rahmioglu N, Zondervan KT. +13 moreeuropepmc +1 more sourceAssociation analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Nature Genetics, 2015 J. Liu, S. van Sommeren, Hailiang Huang, S. Ng, R. Alberts, A. Takahashi, S. Ripke, James C. Lee, L. Jostins, T. Shah, S. Abedian, J. Cheon, Judy H. Cho, N. Daryani, L. Franke, Y. Fuyuno, A. Hart, R. Juyal, G. Juyal, W. Kim, A. Morris, H. Poustchi, W. Newman, V. Midha, T. Orchard, H. Vahedi, A. Sood, J. Sung, R. Malekzadeh, H. Westra, K. Yamazaki, Suk-Kyun Yang, J. Barrett, A. Franke, B. Alizadeh, M. Parkes, T. B K, M. Daly, M. Kubo, C. Anderson, R. Weersma +40 moresemanticscholar +1 more sourceFeasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis +11 morewiley +1 more sourceGenome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Nature Genetics, 2019 R. Karlsson Linnér, Pietro Biroli, Edward Kong, S. Meddens, Robbee Wedow, M. Fontana, M. Lebreton, Stephen P. Tino, A. Abdellaoui, Anke R. Hammerschlag, M. Nivard, A. Okbay, C. A. Rietveld, P. Timshel, M. Trzaskowski, R. Vlaming, C. Zünd, Y. Bao, Laura Buzdugan, Ann H. Caplin, Chia-Yen Chen, P. Eibich, P. Fontanillas, J. González, Peter K. Joshi, V. Karhunen, A. Kleinman, R. Levin, C. Lill, Gerardus A. Meddens, G. Muntané, S. Sanchez-Roige, F. J. Rooij, E. Taskesen, Yang Wu, Futao Zhang, Michelle Babak Robert K. Katarzyna Sarah L. Nicholas A. Kar Agee Alipanahi Bell Bryc Elson Furlotte Huber Litt, M. Agee, B. Alipanahi, R. Bell, K. Bryc, S. Elson, N. Furlotte, K. Huber, N. Litterman, J. McCreight, M. Mcintyre, J. Mountain, C. Northover, S. Pitts, J. Sathirapongsasuti, O. Sazonova, J. Shelton, S. Shringarpure, C. Tian, J. Tung, V. Vacic, C. H. Wilson, Mawussé Habibul Isabel Anand Philip Alexis Frank Marc Dorr Agbessi Ahsan Alves Andiappan Awadalla Battle Beut, M. Agbessi, H. Ahsan, I. Alves, A. Andiappan, P. Awadalla, A. Battle, F. Beutner, Marc Jan Bonder, D. Boomsma, M. Christiansen, A. Claringbould, Patrick Deelen, T. Esko, M. Favé, L. Franke, T. Frayling, S. Gharib, G. Gibson, B. Heijmans, G. Hemani, R. Jansen, M. Kähönen, A. Kalnapenkis, S. Kasela, J. Kettunen, Yungil Kim, H. Kirsten, P. Kovacs, K. Krohn, J. Kronberg-Guzman, V. Kukushkina, Z. Kutalik, Bernett Lee, T. Lehtimäki, M. Loeffler, U. Marigorta, A. Metspalu, L. Milani, G. Montgomery, M. Müller-Nurasyid, M. Nauck, M. Nivard, B. Penninx, M. Perola, N. Pervjakova, B. Pierce, J. Powell, H. Prokisch, B. Psaty, O. Raitakari, S. Ring, S. Ripatti, Olaf Rotzchke, S. Rüeger, A. Saha, M. Scholz, K. Schramm, I. Seppälä, M. Stumvoll, P. Sullivan, P. Hoen, A. Teumer, J. Thiery, L. Tong, A. Tönjes, J. Dongen, J. Meurs, J. Verlouw, P. Visscher, U. Völker, U. Võsa, H. Westra, H. Yaghootkar, Jian Yang, B. Zeng, Aysu Jonathan P. Mark Alan James J. Tune H. Cornelius A Okbay Beauchamp Fontana Lee Pers Rietveld Turley C, A. Okbay, J. Beauchamp, James J. Lee, T. Pers, C. A. Rietveld, P. Turley, Guo-Bo Chen, V. Emilsson, Sven Oskarsson, Joseph K. Pickrell, Kevin Thom, P. Timshel, Ronald de Vlaming, T. Ahluwalia, J. Bacelis, C. Baumbach, G. Bjornsdottir, J. Brandsma, M. P. Concas, J. Derringer, T. Galesloot, G. Girotto, Richa Gupta, Leanne M. Hall, S. Harris, E. Hofer, M. Horikoshi, J. Huffman, Kadri Kaasik, I. Kalafati, R. Karlsson, A. Kong, J. Lahti, S. J. Lee, C. D. de Leeuw, P. Lind, K. Lindgren, Tian Liu, M. Mangino, J. Marten, E. Mihailov, Michael B. Miller, P. J. Most, C. Oldmeadow, A. Payton, W. Peyrot, Yong Qian, R. Rueedi, E. Salvi, B. Schmidt, Katharina E. Schraut, Jianxin Shi, A. Smith, R. Poot, B. S. Pourcain, G. Thorleifsson, N. Verweij, D. Vuckovic, J. Wellmann, Jingyun Yang, Wei Zhao, Zhihong Zhu, B. Alizadeh, N. Amin, A. Bakshi, S. Baumeister, G. Biino, K. Bønnelykke, P. Boyle, H. Campbell, F. Cappuccio, G. Davies, J. De Neve, P. Deloukas, I. Demuth, Jun Ding, L. Eisele, N. Eklund, David M. Evans, J. Faul, M. Feitosa, A. Forstner, I. Gandin, Bjarni Gunnarsson, B. Halldórsson, T. Harris, A. Heath, L. Hocking, E. Holliday, G. Homuth, M. Horan, J. Hottenga, P. D. De Jager, A. Jugessur, M. Kaakinen, S. Kanoni, Liisa Keltigangas-Järvinen, L. Kiemeney, I. Kolčić, S. Koskinen, A. Kraja, M. Kroh, A. Latvala, L. Launer, M. Lebreton, D. Levinson, P. Lichtenstein, P. Lichtner, D. Liewald, A. Loukola, P. Madden, R. Mägi, T. Mäki-Opas, R. Marioni, P. Marques-Vidal, George Mcmahon, C. Meisinger, T. Meitinger, Y. Milaneschi, Ronny Myhre, C. Nelson, D. Nyholt, W. Ollier, A. Palotie, L. Paternoster, N. Pedersen, K. Petrovic, D. Porteous, K. Räikkönen, S. Ring, A. Robino, Olga Rostapshova, I. Rudan, A. Rustichini, V. Salomaa, A. Sanders, Antti-Pekka Sarin, H. Schmidt, R. Scott, Blair H. Smith, Jennifer A. Smith, J. Staessen, E. Steinhagen-Thiessen, K. Strauch, A. Terracciano, M. Tobin, Sheila Ulivi, S. Vaccargiu, L. Quaye, C. Venturini, Anna A. E. Vinkhuyzen, H. Völzke, J. Vonk, D. Vozzi, Johannes Waage, E. Ware, G. Willemsen, J. Attia, D. Bennett, K. Berger, L. Bertram, H. Bisgaard, I. Borecki, U. Bültmann, C. Chabris, F. Cucca, D. Cusi, I. Deary, G. Dedoussis, C. Duijn, J. Eriksson, B. Franke, P. Gasparini, P. Gejman, C. Gieger, H. Grabe, J. Gratten, P. Groenen, V. Gudnason, P. Harst, C. Hayward, D. Hinds, W. Hoffmann, E. Hyppönen, W. Iacono, B. Jacobsson, M. Järvelin, K. Jöckel, J. Kaprio, S. Kardia, Steven F. Lehrer, P. Magnusson, N. Martin, M. McGue, N. Pendleton, N. Pirastu, M. Pirastu, O. Polašek, D. Posthuma, C. Power, M. Province, N. Samani, D. Schlessinger, R. Schmidt, T. Sørensen, T. Spector, K. Stefánsson, U. Thorsteinsdóttir, A. Thurik, N. Timpson, H. Tiemeier, A. Uitterlinden, V. Vitart, P. Vollenweider, D. Weir, James F. Wilson, A. Wright, D. Conley, R. Krueger, G. Smith, A. Hofman, David Laibson, S. Medland, M. Meyer, M. Johannesson, P. Koellinger, D. Cesarini, Daniel J. Benjamin, A. Auton, J. Boardman, D. Clark, Andrew Conlin, Conora Dolan, U. Fischbacher, K. Harris, G. Hasler, M. Ikram, Sonia Jain, R. Karlsson, R. Kessler, M. Kooyman, J. Mackillop, M. Männikkö, C. Morcillo-Suarez, M. McQueen, Klaus M. Schmidt, M. Smart, Matthias Sutter, A. Thurik, Jon White, H. Wit, Jian Yang, E. Fehr, D. Hinds, M. Johannesson, M. Kumari, David Laibson, P. Magnusson, A. Navarro, A. Palmer, D. Posthuma, D. Schunk, M. Stein, R. Svento, H. Tiemeier, P. Timmers, R. Ursano, G. Wagner, James F. Wilson, James J. Lee, Daniel J. Benjamin, J. Beauchamp +406 moresemanticscholar +1 more source
