Results 231 to 240 of about 2,718,862 (371)

Using case‐control designs for genome‐wide screening for associations between genetic markers and disease susceptibility loci [PDF]

open access: bronze, 1999
Quanhe Yang   +5 more
openalex   +1 more source

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1422-1435, May 2025.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

Genetic association study of promoter region polymorphisms in tryptophan hydroxylase and serotonin transporter genes with bipolar disorder [PDF]

open access: bronze, 1998
C. Manzi   +8 more
openalex   +1 more source

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1155-1169, April 2025.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park   +8 more
wiley   +1 more source

Genetic association of the kynurenine pathway to suicidal behavior. [PDF]

open access: yesBrain Behav Immun Health
Tamimou R   +13 more
europepmc   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Association genetic studies in grape

open access: yes, 2008
Association genetic methods, based on the exploitation of linkage disequilibrium (LD), are valuable tools for the dissection of complex traits. In many plant species, they indeed have shown their usefulness for the analysis of the genetic determinism of quantitative traits.
Le Cunff, L.   +20 more
openaire   +3 more sources

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