Results 221 to 230 of about 2,782,325 (342)

Genetic Association Between an AACC Insertion in the 3′UTR of the Stratum Corneum Chymotryptic Enzyme Gene and Atopic Dermatitis [PDF]

, 2004
Yiannis Vasilopoulos, Michael J. Cork, Ruth Murphy, Hywel C Williams, Darren Robinson, Gordon W. Duff, Simon Ward, Rachid Tazi‐Ahnini   +7 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Genetic association of NEAT1 gene polymorphism with the progression of colorectal cancer. [PDF]

J Cancer
Shiu BH, Hsieh YH, Huang CC, Tang CH, Chang LC, Su SC, Yang SF.   +6 more
europepmc   +1 more source

Individualised therapy of angiotensin converting enzyme (ACE) inhibitors in stable coronary artery disease: overview of the primary results of the PERindopril GENEtic association (PERGENE) study [PDF]

, 2011
Jasper J. Brugts, Moniek P.M. de Maat, A.H. Jan Danser, Eric Boersma, Maarten L. Simoons   +4 more
openalex   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Involve Children and Parents in Clinical Studies

Clinical and Translational Science, 2020
Eric Vermeulen, Kim Karsenberg, Johanna H. van derLee, Saskia N. deWildt   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Genetic association and potential mediators between metabolic syndrome and chronic obstructive pulmonary disease: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Zhang Y, Zhang Q.
europepmc   +1 more source

Genome-wide and regional case-control association studies in the genetic analysis of restless legs syndrome

, 2010
Barbara Schormair
openalex   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source