Results 111 to 120 of about 1,290,197 (259)

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Genetic Association Study [PDF]

, 2016
  +4 more sources

Polymorphisms in Corticotrophin-releasing Hormone-proopiomelanocortin (CRH-POMC) System Genes are Associated with Plaque Psoriasis

Acta Dermato-Venereologica, 2019
Tanel Traks, Maris Keermann, Maire Karelson, Ranno Rätsep, Ene Reimann, Helgi Silm, Eero Vasar, Sulev Kõks, Külli Kingo   +8 more
doaj   +1 more source

Population stratification correction using Bayesian shrinkage priors for genetic association studies. [PDF]

Ann Hum Genet, 2023
Liu Z, Turkmen AS, Lin S.
europepmc   +1 more source

Nephrogenic Rests/Nephroblastomatosis in Patients With Unilateral Wilms Tumor Are Not Associated With an Increased Risk of Relapse: An Analysis of Patients Treated on the SIOP‐WT‐2001 Protocol in the SIOP‐UK‐CCLG and SIOP‐GPOH Studies (2001–2022)

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misunderstanding of their diagnostic criteria and terminology.
Gordan M. Vujanić, Rhoikos Furtwängler, Tanzina Chowdhury, Christian Vokuhl, Jenny Wegert, Norbert Graf   +5 more
wiley   +1 more source

Bayes factor for linear mixed model in genetic association studies

Quantitative Biology
Bayes factor has advantages over p‐value as test statistics for association, particularly when comparing multiple non‐nested alternative models.
Yongtao Guan, Daniel Levy
doaj   +1 more source

Variants in candidate genes and their interactions with smoking on the risk of acute coronary syndrome

Biomédica: revista del Instituto Nacional de Salud
Introduction. Multiple genetic and environmental factors interact with the development of acute coronary syndrome. Smoking is one of the environmental factors that might alter the metabolic pathways shared by genes associated with this condition ...
Liliana Franco, Natalia Gallego, Cristian Velarde, Diana Valencia, Juan Pablo Pérez-Bedoya, Kelly Betancur, Kelly Marisancen, Paola Parra, Santiago Carvalho, Luisa Parra, Evert Jiménez, Carlos Martínez, Clara Saldarriaga, Juan Carlos Arango, Nathalia González-Jaramillo, Jenny García, Ana Valencia   +16 more
doaj   +1 more source

Review and further developments in statistical corrections for Winner's Curse in genetic association studies. [PDF]

PLoS Genet, 2023
Forde A, Hemani G, Ferguson J.
europepmc   +1 more source

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley, Ryleigh Krueger, Kellie Joyce, James Stanley, Mary Waskerwitz‐Freyer, Marielle Klunder, David J. Hoogstra   +6 more
wiley   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source