Results 141 to 150 of about 4,028,677 (349)

Circular 92 [PDF]

open access: yes, 1992
The development of improved plant cultivars is accomplished through comprehensive plant breeding programs. Such programs: 1) evaluate promising germplasm to identify superior-performing genotypes for use as parents; 2) create new genetic ...
Blake, Steve A.   +2 more
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Spring Wheat Crosses Trial [PDF]

open access: yes, 2014
On-farm wheat breeding began in Vermont, in cooperation with UVM Extension, in 2007 with a USDA SARE grant to build farmer knowledge in plant breeding.
Blair, Katie   +5 more
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Alternative polyadenylation profiles of susceptible and resistant rice (Oryza sativa L.) in response to bacterial leaf blight using RNA-seq

open access: yesBMC Plant Biology
Background Alternative polyadenylation (APA) is an important pattern of post-transcriptional regulation of genes widely existing in eukaryotes, involving plant physiological and pathological processes.
Shaochun Liu   +10 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Physicochemical Properties of Starch from High-Quality Hybrid Indica Rice: Insights from National High-Quality Rice Gold Award Chinese Varieties

open access: yesFoods
The physicochemical properties of starch in high-quality hybrid indica rice (HQR) varieties that have received the National High-Quality Rice Gold Award are not well characterized.
Yumei Wang   +6 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Breeding and genetics–historical perspective

open access: yesPoultry Science, 1997
This paper is a review of selection methods that have been used in commercial breeding of table egg stocks, broilers, and turkeys, based on the author's experience. In addition, a number of historic developments that have shaped or influenced the selection process are listed and the significance of each is discussed.
openaire   +2 more sources

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