Results 171 to 180 of about 10,408,543 (352)

Genetic characterization and plasma levels of Lyso Gb3 assessed in Fabry disease patients.

open access: yes, 2018
Genetic characterization and plasma levels of Lyso Gb3 assessed in Fabry disease patients.
Elisa Pagnin (5798105)   +9 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Characterization and documentation of genetic resources utilizing multimedia databases: Proceeding of a workshop, 19-20 December 1996, University of Naples Federico II, Naples, Italy

open access: yes, 2019
Advances in information technology have brought image processing and analysis increasingly closer to practical application in a variety of professional fields including plant genetics resources.
Puzone, L.   +2 more
core   +1 more source

Genetic diversity of common beans (Phaseolus vulgaris L.) and runner beans (Phaseolus coccineus L.): a case study from in-situ preserved landraces in Northern Italy

open access: yesFrontiers in Plant Science
IntroductionIn Lombardia region of Italy, several collections of Phaseolus vulgaris and Phaseolus coccineus landraces are conserved in specialized repositories (germplasm banks), yet their morphological characterization and genetic potential remain ...
Alessandra Lezzi   +11 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Characterization of the genetic diversity of Sterechinus neumayeri for West and East Antarctic regions.

open access: yes, 2018
Characterization of the genetic diversity of Sterechinus neumayeri for West and East Antarctic regions.
Angie Díaz (3106245)   +7 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Characterization of non-polio enteroviruses (Picornaviridae, Enterovirus) isolated from clinical specimens and wastewater samples collected in Saint Petersburg and the Leningrad Region

open access: yesВопросы вирусологии
Introduction. Enteroviruses (genus Enterovirus, family Picornaviridae) are one of the common causes of infectious diseases with neurological and dermatological manifestations in children.
Kirill A. Antonenkov   +6 more
doaj   +1 more source

Identification and Functional Characterization of Causative DNA Sequence Variants in Genetic Risk Loci of Periodontitis

open access: yes
IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF CAUSATIVE DNA SEQUENCE VARIANTS IN GENETIC RISK LOCI OF PERIODONTITIS Identification and Functional Characterization of Causative DNA Sequence Variants in Genetic Risk Loci of Periodontitis / Shi, Weiwei
Shi, Weiwei
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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