Genetic Variation in the 3′ Non-Coding Region of Dengue Viruses
Amy C. Shurtleff+11 more
openalex +1 more source
Retraction Note: RNA editing of BFP, a point mutant of GFP, using artificial APOBEC1 deaminase to restore the genetic code. [PDF]
Bhakta S, Sakari M, Tsukahara T.
europepmc +1 more source
Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event
ABSTRACT Objective Phenotype hospital, physician, and emergency department (ED) visits by diagnoses and specialty up to 29 years pre‐multiple sclerosis (MS) onset versus a matched population without MS. Methods We identified people with MS (PwMS) using population‐based administrative data from Ontario, Canada (1991–2020).
Helen Tremlett+8 more
wiley +1 more source
Engineering a controllable and reversible switch for CAR-based cellular immunotherapies via a genetic code expansion system. [PDF]
Liu Y+6 more
europepmc +1 more source
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone+19 more
wiley +1 more source
Evolving Escherichia coli to use a tRNA with a non-canonical fold as an adaptor of the genetic code. [PDF]
Edelmann MP+6 more
europepmc +1 more source
Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan+8 more
wiley +1 more source
Unlocking the genetic code: a comprehensive Genome-Wide association study and gene set enrichment analysis of cell-mediated immunity in chickens. [PDF]
Kianpoor S+4 more
europepmc +1 more source
Genetic Diversity and Expanded Phenotypes in Dystonia: Insights From Large‐Scale Exome Sequencing
ABSTRACT Objective Dystonia is one of the most prevalent movement disorders, characterized by significant clinical and etiological heterogeneity. Despite considerable heritability (~25%), the etiology in most patients remains elusive. Moreover, understanding correlations between clinical manifestations and genetic variants has become increasingly ...
Mirja Thomsen+47 more
wiley +1 more source
Applications of genetic code expansion technology in eukaryotes. [PDF]
Guo QR, Cao YJ.
europepmc +1 more source