Results 51 to 60 of about 6,399 (231)

Genetic and Environmental Sources of Nomophobia: A Small-Scale Turkish Twin Study

open access: yesAddicta: The Turkish Journal on Addictions, 2019
Nomophobia is considered to be a form of behavioral addiction, namely the fear of being out of mobile phone contact. Despite many studies on the prevalence and correlates of mobile phone addiction, not much is known about its etiological nature.
Deniz Deryakulu, Ömer Faruk Ursavaş
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Practical Efficient Regional Land-Use Planning Using Constrained Multi-Objective Genetic Algorithm Optimization

open access: yesISPRS International Journal of Geo-Information, 2021
Practical efficient regional land-use planning requires planners to balance competing uses, regional policies, spatial compatibilities, and priorities across the social, economic, and ecological domains.
Tingting Pan   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Efeito da conexidade de dados sobre a acurácia dos testes de progênie e performance Data connectedness effect on the accuracy of progeny and performance tests

open access: yesRevista Brasileira de Zootecnia, 2001
Dados simulados foram utilizados para verificar o efeito da conexidade sobre a acurácia dos testes de progênie e performance. O genoma simulado foi constituído de uma característica quantitativa governada por 500 locos.
Antonio Policarpo Souza Carneiro   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Stochastic simulation of the influence of insemination on the estimation of breeding value and its reliability

open access: yesCzech Journal of Animal Science, 2007
Insemination is used less commonly in the population of beef cattle than in dairy cattle. As a consequence, herds are genetically isolated and their comparison is difficult.
Z. Veselá   +3 more
doaj   +1 more source

Genome-wide base editor screen identifies regulators of protein abundance in yeast

open access: yeseLife, 2022
Proteins are key molecular players in a cell, and their abundance is extensively regulated not just at the level of gene expression but also post-transcriptionally.
Olga T Schubert   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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