Results 91 to 100 of about 1,829,546 (357)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Genetic selection for temperament traits in dairy and beef cattle

Frontiers in Genetics, 2014
Animal temperament can be defined as a response to environmental or social stimuli. There are a number of temperament traits in cattle that contribute to their welfare, including their response to handling or milking, response to challenge such as human ...
Marie J Haskell, Geoff eSimm, Simon P Turner   +2 more
doaj   +1 more source

The Central role of KNG1 gene as a genetic determinant of coagulation pathway-related traits: Exploring metaphenotypes [PDF]

, 2016
Traditional genetic studies of single traits may be unable to detect the pleiotropic effects involved in complex diseases. To detect the correlation that exists between several phenotypes involved in the same biological process, we introduce ...
Brunel, Helena, Martin-Fernandez, Laura, Martinez Perez, Angel, Massanet, Raimon, Perera Lluna, Alexandre, Soria, José Manuel, Souto, Juan Carlos, Ziyatdinov, Andrey   +7 more
core   +4 more sources

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Non-genetic factor and genetic parameter analysis for growth traits in Sumba Ongole (SO) cattle

Journal of the Indonesian Tropical Animal Agriculture, 2018
The aim of this study was to evaluate non-genetic factors and genetic parameters of the growth traits in Sumba Ongole (SO) cattle. The growth traits were consisted of birth weight (BW), weaning weight (WW), yearling weight (YW), average daily gain of pre-
W.P.B. Putra, P.P. Agung, S. Said
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Genetic parameters for traits evaluated at field tests of 3- and 4-year-old Swedish Warmblood horses

Animal, 2008
There are two types of 1-day field tests available for young Swedish Warmblood sport horses; one test for 3-year olds and one more advanced test for 4-year olds. Conformation, gaits and jumping ability are evaluated at both tests.
Å. Viklund, E. Thorén Hellsten, A. Näsholm, E. Strandberg, J. Philipsson   +4 more
doaj  

Estudo da interação genótipo × ambiente sobre características de crescimento de bovinos de corte utilizando-se inferência bayesiana A study of the genotype × environment interaction for growth traits in beef cattle using Bayesian inference

Revista Brasileira de Zootecnia, 2006
Avaliou-se a interação genótipo × ambiente em um rebanho da raça Canchim por meio de estimativas de parâmetros genéticos dos pesos à desmama e aos 12 meses de idade, do ganho de peso diário entre essas idades e do desempenho estimado por um índice obtido
Arthur dos Santos Mascioli, Maurício Mello de Alencar, Alfredo Ribeiro de Freitas, Elias Nunes Martins   +3 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Genetic correlations between production and disease traits during first lactation in Holstein cows

Animal, 2014
The aim of this study was to estimate genetic correlations between milk yield, somatic cell score (SCS), mastitis, and claw and leg disorders (CLDs) during first lactation in Holstein cows by using a threshold–linear random regression test-day model.
K. Hagiya, T. Yamazaki, Y. Nagamine, K. Togashi, S. Yamaguchi, Y. Gotoh, T. Kawahara, Y. Masuda, M. Suzuki   +8 more
doaj