Results 71 to 80 of about 5,517,316 (290)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Genetic and Phenotypic Parameter Estimates of Body Weight and Egg Production Traits of Tilili Chicken in Ethiopia

open access: yesAnimals
High genetic variation in African indigenous chicken populations provides opportunities for long-term genetic improvement. This study estimated genetic parameters for economic traits based on data derived from a nucleus flock comprising two generations ...
Birhan Kassa   +9 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Genetic Parameters of the Growth Rate, Survival Rate and Feed Efficiency Ratio of Turbot (Scophthalmus maximus) at an Early Growth Stage

open access: yesAnimals
Genetic improvement, including improving the growth rate, survival rate and feed efficiency ratio (FER), can maximize the production efficiency of turbot.
Donghui Gou   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Genomic prediction of genotyped and non-genotyped Jeju black cattle using single- and multi-trait methods for carcass traits

open access: yesItalian Journal of Animal Science
Jeju black cattle (JBC) are recognised as one of Korea’s native breeds that are well-suited to the local environmental conditions and known for their excellent meat quality.
Md Azizul Haque   +4 more
doaj   +1 more source

Genetic background of behavior traits in lactating sows under heat-stress conditions and their relationship with heat tolerance and maternal performance traits

open access: yesFrontiers in Genetics
Heat stress is among the most significant welfare challenges facing modern swine production systems worldwide. Pigs are particularly susceptible to heat stress due to their inactive sudoriferous glands, which limits their capacity for evaporative cooling.
Sharlene O. Hartman   +11 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Genetic Analysis of Stayability and its Relationships with Production, Conformation, Fertility and Health Traits in Holstein Cattle

open access: yesVeterinary Sciences
The objectives of this study were to estimate genetic parameters for stayability in Chinese Holstein cattle and to estimate its genetic correlations with routinely collected traits.
Honghong Hu   +7 more
doaj   +1 more source

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