Results 61 to 70 of about 1,008,628 (263)

Genomic prediction of genotyped and non-genotyped Jeju black cattle using single- and multi-trait methods for carcass traits

open access: yesItalian Journal of Animal Science
Jeju black cattle (JBC) are recognised as one of Korea’s native breeds that are well-suited to the local environmental conditions and known for their excellent meat quality.
Md Azizul Haque   +4 more
doaj   +1 more source

Genetic background of behavior traits in lactating sows under heat-stress conditions and their relationship with heat tolerance and maternal performance traits

open access: yesFrontiers in Genetics
Heat stress is among the most significant welfare challenges facing modern swine production systems worldwide. Pigs are particularly susceptible to heat stress due to their inactive sudoriferous glands, which limits their capacity for evaporative cooling.
Sharlene O. Hartman   +11 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Genetic Analysis of Stayability and its Relationships with Production, Conformation, Fertility and Health Traits in Holstein Cattle

open access: yesVeterinary Sciences
The objectives of this study were to estimate genetic parameters for stayability in Chinese Holstein cattle and to estimate its genetic correlations with routinely collected traits.
Honghong Hu   +7 more
doaj   +1 more source

Contribution of different yield components for grain yield improvement in Maize (Zea mays L.) [PDF]

open access: yesElectronic Journal of Plant Breeding, 2012
Seventy two maize (Zea mays L.) hybrids along with their parental lines were assessed for genetic correlation among 14quantitative traits. All the traits studied exhibited a positive and significant correlation with grain yield except days to tasselling ...
S.Kanagarasu*, G.Nallathambi, K.N.Ganesan and S.Kannan
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Variability of fibre quality on Chinese Alashan Left Banner White Cashmere goat

open access: yesItalian Journal of Animal Science, 2018
The heritability and the phenotypic and genetic correlations of down weight (DW), down fibre diameter (DFD), and coefficient of variation of the down fibre diameter (CVDFD) of Chinese Alashan Left Banner White Cashmere goat were estimated on 1375 one ...
Stefano Pallotti   +7 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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