Results 61 to 70 of about 5,517,316 (290)

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Estimating heritability in honeybees: Comparison of three major methods based on empirical and simulated datasets

Ecology and Evolution, 2021
The genetic contribution to phenotypic variation (namely the heritability) affects the response to selection. In honeybee, the haplodiploid sex determination does not allow the straightforward use of classical quantitative genetics methods to estimate ...
Hélène Jourdan‐Pineau, Gaëlle Antoine, Julien Galataud, Hélène Delatte, Christophe Simiand, Johanna Clémencet   +5 more
doaj   +1 more source

Estimates of Genetic Parameters for Milk, the Occurrence of and Susceptibility to Clinical Lameness and Claw Disorders in Dairy Goats

Animals, 2023
The New Zealand goat industry accesses niche markets for high-value products, mainly formula for infants and young children. This study aimed to estimate the genetic parameters of occurrence and susceptibility of clinical lameness and selected claw ...
Natasha Jaques, Sally-Anne Turner, Emilie Vallée, Cord Heuer, Nicolas Lopez-Villalobos   +4 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Genetic Analysis of Cortical Thickness and Fractional Anisotropy of Water Diffusion in the Brain

Frontiers in Neuroscience, 2011
ObjectivesThe thickness of the brain’s cortical gray matter (GM) and the fractional anisotropy (FA) of the cerebral white matter (WM) each follow an inverted U-shape trajectory with age.
Peter eKochunov, Peter eKochunov, Peter eKochunov, David eGlahn, David eGlahn, Tom eNichols, Anderson eWinkler, Elliott eHong, Henry eHolcomb, Jason eStein, Paul eThompson, Joanne eCurran, Melany eCarless, Rene eOlvera, MP eJohnson, Shelley eCole, Valeria eKochunov, Jack eKent, John eBlangero   +18 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Estimation of genetic parameters for milking temperament in Holstein-Gyr cows

Frontiers in Animal Science, 2023
IntroductionDairy cattle with poor temperament can cause several inconveniences during milking, leading to labor difficulties, increasing the risk of accidents with animals and workers, and compromising milk yield and quality.
Paula A. Batista Taborda, Paula A. Batista Taborda, Tiago da Silva Valente, Monique Valéria de Lima Carvalhal, Marcos Vinicius Gualberto Barbosa da Silva, Mateus J. R. Paranhos da Costa   +5 more
doaj   +1 more source

THE EVOLUTION OF GENETIC CORRELATIONS: AN ANALYSIS OF PATTERNS [PDF]

Evolution, 1996
The genetic correlation is a central parameter of quantitative genetics, providing a measure of the rate at which traits respond to indirect selection (i.e., selection that does not act upon the traits under study, but some other trait with which they have genes in common).
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Vascular endothelial growth factor and risk of malignant brain tumor: A genetic correlation and two-sample Mendelian randomization study

Frontiers in Oncology, 2023
ObjectiveThe relationship between vascular endothelial growth factor (VEGF) and the risk of malignant brain tumors has always been a concern in the medical field.
Qiaoyun Zhang, Qiaoyun Zhang, Guangheng Wu, Xiaoyu Zhang, Xiaoyu Zhang, Jie Zhang, Mengyang Jiang, Yiqiang Zhang, Lixiang Ding, Youxin Wang   +9 more
doaj   +1 more source