Results 61 to 70 of about 1,946,419 (298)

Genetic Relationship Between Endometriosis and Melanoma

Frontiers in Reproductive Health, 2021
Epidemiological studies have observed that risk of endometriosis is associated with history of cutaneous melanoma and vice versa. Evidence for shared biological mechanisms between the two traits is limited.
Fei Yang, Sally Mortlock, Stuart MacGregor, Mark M. Iles, Mark M. Iles, Maria Teresa Landi, Jianxin Shi, Matthew H. Law, Matthew H. Law, Grant W. Montgomery   +9 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Genetic Determinism Exists for the Global DNA Methylation Rate in Sheep

Frontiers in Genetics, 2020
Recent studies showed that epigenetic marks, including DNA methylation, influence production and adaptive traits in plants and animals. So far, most studies dealing with genetics and epigenetics considered DNA methylation sites independently.
Dominique Hazard, Florence Plisson-Petit, Carole Moreno-Romieux, Stéphane Fabre, Laurence Drouilhet   +4 more
doaj   +1 more source

Joint Analysis of Genetic Correlation, Mendelian Randomization and Colocalization Highlights the Bi-Directional Causal Association Between Hypothyroidism and Primary Biliary Cirrhosis

Frontiers in Genetics, 2021
Background: Hypothyroidism and primary biliary cirrhosis (PBC) are often co-existed in observational epidemiological studies. However, the causal relationship between them remains unclear.Methods: Genetic correlation, Mendelian randomization (MR) and ...
Yanjun Wang, Ping Guo, Yanan Zhang, Lu Liu, Ran Yan, Zhongshang Yuan, Yongfeng Song, Yongfeng Song, Yongfeng Song   +8 more
doaj   +1 more source

Estimates of Genetic and Phenotypic Trends of Growth Traits in Bali Cattle [PDF]

, 2012
The aim of this study was to estimate genetic and phenotypic trends for growth traits including birth (BW), weaning (WW) and yearling weight (YW) in Bali cattle.
Gunawan, A. (A), Jakaria, J. (Jakaria), Sari, R. (R)   +2 more
core  

Climatic niche and neutral genetic diversity of the six Iberian pine species: a retrospective and prospective view [PDF]

, 2010
Quaternary climatic fluctuations have left contrasting historical footprints on the neutral genetic diversity patterns of existing populations of different tree species.
Soto de Viana, Álvaro
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Heritability of problem drinking and the genetic overlap with personality in a general population sample

Frontiers in Genetics, 2011
This study examined the heritability of problem drinking and investigated the phenotypic and genetic relationships between problem drinking and personality. It was conducted in a sample of 5,870 twins and siblings and 4,420 additional family members from
Marleen H.M. De Moor, Marleen H.M. De Moor, Jacqueline M. Vink, Jacqueline M. Vink, Jenny H.D.A. van Beek, Jenny H.D.A. van Beek, Lot M. Geels, Lot M. Geels, Meike eBartels, Meike eBartels, Meike eBartels, Eco J.C. de Geus, Eco J.C. de Geus, Eco J.C. de Geus, Gonneke eWillemsen, Gonneke eWillemsen, Gonneke eWillemsen, Dorret I. Boomsma, Dorret I. Boomsma, Dorret I. Boomsma   +19 more
doaj   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Weighting factors of sire daughter information in international genetic evaluations [PDF]

, 2001
International genetic evaluations of dairy bulls are currently based on national genetic evaluation results. Total number of daughters in a country is used to weight national information, but may not optimally reflect the precision of a sire's daughter ...
Banos, G, Fikse, WF
core   +1 more source