Results 51 to 60 of about 5,517,316 (290)

Genetic Relationship Between Endometriosis and Melanoma

Frontiers in Reproductive Health, 2021
Epidemiological studies have observed that risk of endometriosis is associated with history of cutaneous melanoma and vice versa. Evidence for shared biological mechanisms between the two traits is limited.
Fei Yang, Sally Mortlock, Stuart MacGregor, Mark M. Iles, Mark M. Iles, Maria Teresa Landi, Jianxin Shi, Matthew H. Law, Matthew H. Law, Grant W. Montgomery   +9 more
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Genetic Relationship of Body Energy and Blood Metabolites with Reproduction in Holstein Cows [PDF]

, 2008
Body condition score (BCS), energy content (EC), cumulative effective energy balance (CEEB), and blood serum concentrations of glucose, beta-hydroxybutyrate (BHBA), and nonesterified fatty acids ( NEFA) were measured throughout first lactation in 497 ...
Arsenos, G., Zygoyiannis, D., Oikonomou, G., Valergakis, G. E., Banos, G., Tsiaras, A.   +5 more
core   +1 more source

A re-formulation of generalized linear mixed models to fit family data in genetic association studies

Frontiers in Genetics, 2015
The generalized linear mixed model (GLMM) is a useful tool for modeling genetic correlation among family data in genetic association studies. However, when dealing with families of varied sizes and diverse genetic relatedness, the GLMM has a special ...
Tao eWang, Peng eHe, Peng eHe, Kwang Woo eAhn, Xujing eWang, Soumitra eGhosh, Purushottam eLaud   +6 more
doaj   +1 more source

Genetic Determinism Exists for the Global DNA Methylation Rate in Sheep

Frontiers in Genetics, 2020
Recent studies showed that epigenetic marks, including DNA methylation, influence production and adaptive traits in plants and animals. So far, most studies dealing with genetics and epigenetics considered DNA methylation sites independently.
Dominique Hazard, Florence Plisson-Petit, Carole Moreno-Romieux, Stéphane Fabre, Laurence Drouilhet   +4 more
doaj   +1 more source

Joint Analysis of Genetic Correlation, Mendelian Randomization and Colocalization Highlights the Bi-Directional Causal Association Between Hypothyroidism and Primary Biliary Cirrhosis

Frontiers in Genetics, 2021
Background: Hypothyroidism and primary biliary cirrhosis (PBC) are often co-existed in observational epidemiological studies. However, the causal relationship between them remains unclear.Methods: Genetic correlation, Mendelian randomization (MR) and ...
Yanjun Wang, Ping Guo, Yanan Zhang, Lu Liu, Ran Yan, Zhongshang Yuan, Yongfeng Song, Yongfeng Song, Yongfeng Song   +8 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

A new genetic algorithm for multi-label correlation-based feature selection. [PDF]

, 2015
This paper proposes a new Genetic Algorithm for Multi-Label Correlation-Based Feature Selection (GA-ML-CFS). This GA performs a global search in the space of candidate feature subset, in order to select a high-quality feature subset is used by a multi ...
Jungjit, Suwimol, Freitas, Alex A.
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Heritability of problem drinking and the genetic overlap with personality in a general population sample

Frontiers in Genetics, 2011
This study examined the heritability of problem drinking and investigated the phenotypic and genetic relationships between problem drinking and personality. It was conducted in a sample of 5,870 twins and siblings and 4,420 additional family members from
Marleen H.M. De Moor, Marleen H.M. De Moor, Jacqueline M. Vink, Jacqueline M. Vink, Jenny H.D.A. van Beek, Jenny H.D.A. van Beek, Lot M. Geels, Lot M. Geels, Meike eBartels, Meike eBartels, Meike eBartels, Eco J.C. de Geus, Eco J.C. de Geus, Eco J.C. de Geus, Gonneke eWillemsen, Gonneke eWillemsen, Gonneke eWillemsen, Dorret I. Boomsma, Dorret I. Boomsma, Dorret I. Boomsma   +19 more
doaj   +1 more source