Most of the genetic covariation between major depressive and alcohol use disorders is explained by trait measures of negative emotionality and behavioral control [PDF]
Background Mental health disorders commonly co-occur, even between conceptually distinct syndromes, such as internalizing and externalizing disorders.
Ellingson, J. M +4 more
core +3 more sources
Purpose: Observational studies have suggested a protective effect of alcohol intake with autoimmune disorders, which was not supported by Mendelian randomization (MR) analyses that used only a few (<20) instrumental variables.Methods: We systemically ...
Xia Jiang +6 more
doaj +1 more source
Isolation by distance in a population of a small land snail Trochoidea geyeri : evidence from direct and indirect methods [PDF]
Population structure was estimated in a continuous population of a small land snail (Trochoidea geyeri). Mark-recapture experiments and randomly amplified polymorphic DNA analyses indicate that the population structure can be described by the isolation ...
Bahl, Andreas +2 more
core +1 more source
BackgroundStroke in UK Biobank (UKB) is ascertained via linkages to coded administrative datasets and self-report. We studied the accuracy of these codes using genetic validation.MethodsWe compiled stroke-specific and broad cerebrovascular disease (CVD ...
Kristiina Rannikmäe +19 more
doaj +1 more source
Identifying progressive imaging genetic patterns via multi-task sparse canonical correlation analysis: a longitudinal study of the ADNI cohort [PDF]
Motivation Identifying the genetic basis of the brain structure, function and disorder by using the imaging quantitative traits (QTs) as endophenotypes is an important task in brain science.
Du, Lei +7 more
core +1 more source
The Genetic and Environmental Sources of Resemblance Between Normative Personality and Personality Disorder Traits [PDF]
Recent work has suggested a high level of congruence between normative personality, most typically represented by the big five factors, and abnormal personality traits.
Aggen, S. H. +8 more
core +2 more sources
Environmental stress alters genetic regulation of novelty seeking in vervet monkeys. [PDF]
Considerable attention has been paid to identifying genetic influences and gene-environment interactions that increase vulnerability to environmental stressors, with promising but inconsistent results.
Bailey, JN +5 more
core +1 more source
Evocative gene-environment correlation between genetic risk for schizophrenia and bullying victimization [PDF]
Bullying exposure concerns over 10% of adolescents in Europe. Moreover, bullying victimization is heritable and victims are liable to psychotic symptoms, partly because of shared heritability with psychosis.
Bertolino, A. +6 more
core +2 more sources
AN EXPERIMENTAL EVALUATION OF GENETIC CORRELATION [PDF]
ABSTRACT Heritability and genetic correlations realized from both single-trait and antagonistic index selection were compared with paternal half-sib estimates. Primary attention was focused on the genetic correlation between six-week body weight and six-week tail length.
J J, Rutledge, E J, Eisen, J E, Legates
openaire +2 more sources
Genetic parameters of growth traits of sheep reared in Africa. A review Introduction. Due to the importance of sheep farming, the genetic parameters of the growth traits of several breeds in Africa have been estimated and reported in various ...
Ramsès Monkotan +2 more
doaj +1 more source

