Results 101 to 110 of about 1,122,121 (342)

Random regression models with B-splines to estimate genetic parameters for body weight of young bulls in performance tests

open access: yesRevista Brasileira de Zootecnia, 2018
The objective of this study was to estimate genetic parameters for body weight of beef cattle in performance tests. Different random regression models with quadratic B-splines and heterogeneous residual variance were fitted to estimate covariance ...
Daiane Cristina Becker Scalez   +5 more
doaj   +1 more source

Genetic correlations in the rhesus macaque dentition

open access: yesJournal of Human Evolution, 2020
Quantitative genetic analyses can indicate how complex traits respond to natural selection by demonstrating the genetic relationships between features that constrain their evolution. Genetic correlations between dental measurements have been estimated previously in baboons, humans, and tamarins and indicate variable patterns of modularity by tooth type
openaire   +4 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Potencial produtivo de progênies de feijão-caupi com arquitetura ereta de planta Potential grain yield of cowpea progenies with erect plant type

open access: yesCiência Rural, 2009
O objetivo foi estimarem-se parâmetros genéticos e identificarem-se, em populações de feijão-caupi, genótipos promissores quanto à produtividade de grãos e arquitetura ereta de planta.
Carlos Humberto Aires Matos Filho   +4 more
doaj   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

System-Level Genetic Codes: An Explanation for Biological Complexity [PDF]

open access: yesarXiv, 2000
Complex systems with tightly coadapted parts frequently appear in living systems and are difficult to account for through Darwinian evolution, that is random variation and natural selection, if the constituent parts are independently coded in the genetic code.
arxiv  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Genotype by environment interaction in Nelore cattle from five Brazilian states

open access: yesGenetics and Molecular Biology, 2011
Records from 75,941 Nelore cattle were used to determine the importance of genotype by environment interaction (GEI) in five Brazilian states. (Co)variance components were estimated by single-trait analysis (with yearling weight, W450, considered to be ...
Iara Del Pilar Solar Diaz   +3 more
doaj  

Associations among growth, scrotal circumference, and visual score of beef cattle in performance tests on pasture or in feedlots

open access: yesRevista Brasileira de Zootecnia
This study aimed to evaluate associations among final weight (FW), average daily gain (ADG), scrotal circumference (SC), and visual score (VS) of beef cattle in performance tests on pasture or in feedlots.
Fernanda Santos Silva Raidan   +7 more
doaj   +1 more source

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