Results 161 to 170 of about 7,495,262 (331)

Cultural Inheritance, Gender, and Intergenerational Occupational Mobility: Evidence from a Developing Economy [PDF]

This paper presents evidence on intergenerational occupational mobility from agriculture to the nonfarm sector using survey data from Nepal with a focus on the role played by cultural inheritance and gender norms.
Forhad Shilpi, M. Shahe Emran
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

PARÁMETROS GENÉTICOS PARA CARACTERÍSTICAS REPRODUCTIVAS EN UNA POBLACIÓN DE BÚFALOS (BUBALUS BUBALIS ARTIODACTYLA, BOVIDAE) EN EL MAGDALENA MEDIO COLOMBIANO GENETIC PARAMETERS FOR REPRODUCTIVE TRAITS IN A POPULATION OF BUFFALOES (BUBALUS BUBALIS ARTIODACTYLA: BOVIDAE) IN THE MIDDLE MAGDALENA REGION OF COLOMBIA

Revista Facultad Nacional de Agronomía Medellín, 2010
La investigación se hizo para estimar los componentes de (co)varianza y parámetros genéticos para edad al primer parto (EPP) e intervalo entre partos (IEP) en una población bufalina en el Magdalena Medio Colombiano.
Diana María Bolívar Vergara, Edison Julián Ramírez Toro, Divier Antonio Agudelo Gómez, Roberto Arturo Angulo Arroyave, Mario Fernando Cerón Muñoz   +4 more
doaj  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Genetic parameters for five traits in Africanized honeybees using Bayesian inference

Genetics and Molecular Biology, 2013
Heritability and genetic correlations for honey (HP) and propolis production (PP), hygienic behavior (HB), syrupcollection rate (SCR) and percentage of mites on adult bees (PMAB) of a population of Africanized honeybees were estimated.
Alessandro Haiduck Padilha, Aroni Sattler, Jaime Araújo Cobuci, Concepta Margaret McManus   +3 more
doaj  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

The Casual Associations Between Brain Functional Networks and Fibromyalgia: A Large-Scale Genetic Correlation and Mendelian Randomization Study

Bioengineering
While the central mechanisms of fibromyalgia have gained attention, the causal effects between brain networks and fibromyalgia remain unclear. Two-sample Mendelian randomization and Linkage Disequilibrium Score Regression were performed to investigate ...
Yiqun Hu, Guang Yang, Zhenhan Deng, Shengwu Yang, Yusheng Li, Wenfeng Xiao, Bangbao Lu, Xiongbai Zhu   +7 more
doaj   +1 more source

Locomotion in Response to Shifting Climate Zones: Not So Fast [PDF]

, 2010
Although a species’ locomotor capacity is suggestive of its ability to escape global climate change, such a suggestion is not necessarily straightforward. Species vary substantially in locomotor capacity, both ontogenetically and within/among populations,
Feder, Martin E., Garland, Theodore, Jr., Marden, James H., Zera, Anthony J.   +3 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source