Results 291 to 300 of about 7,495,262 (331)

Estimating genetic correlations

Annals of Human Genetics, 1980
A method is proposed for simultaneous estimation of genetical variance and covariance components for quantitative characters and hence correlations and cross-correlations between relatives. It proceeds by successive approximations, which are not difficult to compute. Judging by examples, they appear to converge rapidly in practice.
openaire   +2 more sources

Genetic correlations in validating emotionality

Behavior Genetics, 1990
Sixty-six rats of seven inbred strains were observed in an open field (OF) and in a light-dark preference box (LDB). Each set of apparatus provides measures of locomotor activity and of the time spent in the "most protected" area (the corners in the OF, the dark compartment in the LDB). These measures are proposed to be indices of emotionality.
F J, van der Staay, S, Kerbusch, W, Raaijmakers   +2 more
openaire   +2 more sources

Genetic correlates of efavirenz hypersusceptibility

AIDS, 2004
Non-nucleoside reverse transcriptase inhibitor (NNRTI) hypersusceptibility is seen in approximately 30% of HIV isolates with nucleoside reverse transcriptase inhibitor (NRTI) resistance. NNRTI hypersusceptibility has been associated with improved outcomes to NNRTI-based therapy.To determine the genetic correlates of efavirenz hypersusceptibility.Paired
Nancy S, Shulman, Ronald J, Bosch, John W, Mellors, Mary A, Albrecht, David A, Katzenstein   +4 more
openaire   +2 more sources

Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images

Science, 2023
Cardiovascular health interacts with cognitive and mental health in complex ways, yet little is known about the phenotypic and genetic links of heart-brain systems.
Bingxin Zhao, Tengfei Li, Zirui Fan, Yue Yang, Juan Shu, Xiaochen Yang, Xifeng Wang, T. Luo, Jiarui Tang, D. Xiong, Zhenyi Wu, Bingxuan Li, Jie Chen, Y. Shan, Chal E. Tomlinson, Ziliang Zhu, Yun Li, J. Stein, Hongtu Zhu   +18 more
semanticscholar   +1 more source

Inference about genetic correlations

Behavior Genetics, 1988
In polygenic systems genetic correlations and the factors and specific genetic variances from genetic correlation matrices are often interpreted in terms of sets of genes common or specific to variables. While these inferences may indeed be true, a genetic correlation is not always sufficient evidence for the inferences.
openaire   +2 more sources

Genetic Correlates of Adult Attachment Style

Personality and Social Psychology Bulletin, 2008
Attachment theory attempts to explain effects of social experiences, not genes, on personality development. Most studies of the development of attachment insecurities support this emphasis on social experiences rather than genes, although there are exceptions.
Omri, Gillath, Phillip R, Shaver, Jong-Min, Baek, David S, Chun   +3 more
openaire   +2 more sources

Genetic correlations with ethanol withdrawal severity

Pharmacology Biochemistry and Behavior, 1983
A major goal of pharmacogenetic research on alcoholism remains the identification of some "marker" that could predict the liability of a particular individual for a genetic susceptibility to develop alcoholism. The present paper presents evidence that the severity of withdrawal from physical dependence on ethanol varies widely among inbred strains of ...
J C, Crabbe, E R, Young, A, Kosobud
openaire   +2 more sources

Genetic correlates of insight in schizophrenia

Schizophrenia Research, 2018
Insight in schizophrenia is clinically important as it is associated with several adverse outcomes. Genetic contributions to insight are unknown. We examined genetic contributions to insight by investigating if polygenic risk scores (PRS) and candidate regions were associated with insight.Schizophrenia case-only analysis of the Clinical Antipsychotics ...
Rose Mary Xavier, Allison Vorderstrasse, Richard S.E. Keefe, Jennifer R. Dungan   +3 more
openaire   +2 more sources

Oligodendrogliomas: clinical and genetic correlations

Current Opinion in Neurology, 2001
Oligodendrogliomas, once obscure, are now recognized as a relatively common form of primary brain tumour, and are among the most chemosensitive of all solid human malignancies. New histopathological, molecular, and genetic information has, for the first time, allowed the distinction of several subtypes of human glioma with predictable biological and ...
openaire   +2 more sources

Genetic Correlations with Multiple Alleles

Biometrics, 1960
Hogben [1932] gave the values for filial and fraternal correlations for matings involving two alleles in a panmictic population. The subject has been considered in great detail by Li [1955], but the known results are restricted to the case of two alleles. Consequently, if it is desired to compare a correlation derived from actual experimental data with
openaire   +1 more source