Results 71 to 80 of about 384,345 (264)

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna, Alexia Muresan, Estelle Lecluze, Karine Leduc, Nathalie Fournier, Maria Tamer, Jean‐François Delisle, Jeremi Charbonneau, Annie Viau, Jessica Darilus, Marie‐Joëlle Doré‐Bergeron, Valérie Arsenault, Evelyne Doyon‐Trottier, Stéphanie Forte, Nancy Robitaille, Yves Pastore, Thomas Pincez   +16 more
wiley   +1 more source

Heritability Estimates of Behavioral Traits and Their Genetic Relationships with Performance Traits in Japanese Quail

Animals
The present study aimed to estimate the heritabilities of behavioral, growth, carcass, and growth curve traits and to determine the genetic and phenotypic relationships among these traits in Japanese quail (Coturnix japonica). A total of 500 quail chicks
Esra Karaduman, Doğan Narinç, Ali Aygun   +2 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Genetic correlations in the rhesus macaque dentition

Journal of Human Evolution, 2020
Quantitative genetic analyses can indicate how complex traits respond to natural selection by demonstrating the genetic relationships between features that constrain their evolution. Genetic correlations between dental measurements have been estimated previously in baboons, humans, and tamarins and indicate variable patterns of modularity by tooth type
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Genetic variation in Araucaria cunninghamii provenances in Luiz Antonio-SP, Brazil

Crop Breeding and Applied Biotechnology, 2005
The genetic variation in traits of growth and shape and their distribution among and within ten Australian provenances of Araucaria cunninghamii was studied under the environmental conditions of Luiz Antonio, state of São Paulo (SP).
Alexandre Magno Sebbenn, Antonio Carlos Scatena Zanatto, Miguel Luiz Menezes Freitais, Aida Sanae Sato, Lígia de Castro Ettori   +4 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The fecal microbiota of Holstein cows is heritable and genetically correlated to dairy performances

Journal of Dairy Science
: The fecal microbiota of ruminants constitutes a diversified community that has been phenotypically associated with a variety of host phenotypes, such as production and health.
L. Brulin, S. Ducrocq, J. Estellé, G. Even, S. Martel, S. Merlin, C. Audebert, P. Croiseau, M.-P. Sanchez   +8 more
doaj   +1 more source

Parâmetros genéticos e tendências genéticas e fenotípicas para características produtivas e de conformação na fase pré-desmama em uma população da raça Aberdeen Angus Genetic parameters and genetic and phenotypic trends for pre-weaning productive and conformation traits for an Aberdeen Angus breed population

Revista Brasileira de Zootecnia, 2009
Com os objetivos de estimar parâmetros genéticos e avaliar a tendência genética e a fenotípica para as características peso ao nascer (PN), ganho médio diário do nascimento à desmama (GMDND), peso à desmama ajustado para 205 dias (P205) e para os escores
Tomás Weber, Paulo Roberto Nogara Rorato, Jader Silva Lopes, Juliana Grigolleto Comin, Mariana de Almeida Dornelles, Ronyere Olegário de Araújo   +5 more
doaj   +1 more source