Results 81 to 90 of about 384,345 (264)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Number of recombinations and genetic properties of a maize population undergoing recurrent selection Número de recombinações e as propriedades genéticas de uma população de milho sob seleção recorrente

open access: yesScientia Agricola, 2009
In maize recurrent selection programs, selected genotypes were recombined once to generate genetic variability for the next selection cycle.
Francisco Pinheiro Lima Neto   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Análise genética do período de gestação em animais de um rebanho Canchim: estimação de parâmetros genéticos e escolha entre modelos animais alternativos Genetic analysis of gestation period in a Canchim beef cattle herd: estimation of genetic parameters and choice among alternative animal models

open access: yesRevista Brasileira de Zootecnia, 2011
Os objetivos neste trabalho foram comparar modelos animais alternativos para a análise do período de gestação e verificar se essa característica possui variabilidade genética suficiente para ser incluída em programas de seleção, por meio de estimativas ...
Talita Buttarello Mucari   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

An Ecological-Evolutionary Investigation of Phenotypic, Genetic, and Environmental Variation and Correlations Among Reproductive Traits of Tall Goldenrod (Solidago altissima)

open access: yesPlants
Although fitness-related traits are expected to be under strong selection, traits related to reproduction are often quite variable within plant populations.
Michael Wise   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Senescence and the Genetic-Correlation Hang-Up

open access: yesThe American Naturalist, 1987
Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire   +1 more source

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