Results 111 to 120 of about 207,733 (353)

Aspectos éticos y legales del asesoramiento genético [PDF]

open access: yes, 2005
The genetic data have some features that makes necessary to protect it more than other individual data. There is a wide legal framework related to human genetic data that takes in account this ?excepcionalism?.
Brunet i Vidal, Joan
core   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Genetic Counseling in Renal Masses

open access: yesAdvances in Urology, 2008
All urologists have faced patients suffering a renal cancer asking for the occurrence of the disease in their offspring and very often the answer to this question has not been well founded from the scientific point of view, and only in few cases a ...
José Antonio López-Guerrero   +3 more
doaj   +1 more source

Genetic Counselling in X-Linked Eye Diseases [PDF]

open access: bronze, 1973
J. François   +3 more
openalex   +1 more source

Genetic counselling [PDF]

open access: yesBMJ, 1988
J G, Thornton, R J, Lilford
openaire   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Pediatric residents\u27 use of jargon during counseling about newborn genetic screening results [PDF]

open access: yes, 2008
OBJECTIVE. The goal was to investigate pediatric residents’ usage of jargon during discussions about positive newborn screening test results. METHODS.
Christopher, Stephanie   +3 more
core   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Ethnic Identity and Teratogenic Risk Perceptions [PDF]

open access: yes, 2016
Elevated perceptions of teratogenic risk can cause anxiety and confusion among pregnant women. To assess whether ethnic identity and demographic factors can influence teratogenic risk perceptions, 194 pregnant women in Houston were surveyed using the ...
Chan, Katie M
core   +1 more source

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