Results 71 to 80 of about 2,249,426 (311)

What Information Do Cancer Genetic Counselees Prioritize?

, 2011
This study explored the informational needs of individuals attending genetic counseling for hereditary cancer, using a free-choice and a forced choice method. Prior to the consultation the informational needs of 334 counselees from Sweden and Norway were
Ingvoldstad, Charlotta,, Lampic, C,, Ingvoldstad, C, Afsaneh Hayat Roshanai, Nordin, Karin,, Rosenquist, Richard, Claudia Lampic, Lampic, Claudia,, Bjorvatn, C, Roshanai, AH, Bjorvatn, Chathrine,, Stenmark Askmalm, Marie, Stenmark-Askmalm, Marie,, Hayat Roshanai, Afsaneh, Rosenquist, R, Askmalm, MS, Ingvoldstad, Charlotta, Richard Rosenquist, Marie Stenmark Askmalm, Hayat Roshanai, Afsaneh,, Bjorvatn, Chathrine, Charlotta Ingvoldstad, Chathrine Bjorvatn, Askmalm, Marie Stenmark, Rosenquist, Richard,, Karin Nordin, Nordin, Karin, Nordin, K   +27 more
core   +1 more source

Clinical genetic counselor experience in the adoption of telehealth in the United States and Canada during the COVID‐19 pandemic

, 2021
The COVID‐19 pandemic has significantly impacted the service delivery model (SDM) of clinical genetic counseling across the United States and Canada. A cross‐sectional survey was distributed to 4,956 genetic counselors (GCs) from the American Board of ...
James M. Mirocha, Ahimaz, Priyanka R., Ma, Daria, Mohan, Pooja, Jessica L. Giordano, Cook, Lola, Lola Cook, Daria Ma, Stephanie A. Cohen, Priyanka R. Ahimaz, Giordano, Jessica L., Cohen, Stephanie A., Mirocha, James M., Pooja Mohan   +13 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Predictors of Heart‐Focused Anxiety in Patients Undergoing Genetic Investigation and Counseling of Long QT Syndrome or Hypertrophic Cardiomyopathy: A One Year Follow‐up

, 2011
Since Long QT syndrome and Hypertrophic cardiomyopathy are inherited cardiac disorders that may cause syncope, palpitations, serious arrhythmias, and sudden cardiac death, at-risk individuals may experience heart-focused anxiety.
Bjorvatn, Cathrine, Rokne, Berit, Nina Øyen, Berit Rokne, Oyen, Nina, Geir Egil Eide, Nordin, Karin,, Anniken Hamang, Karin Nordin, Cathrine Bjorvatn, Eide, Geir Egil, Hamang, Anniken   +11 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

THE FREQUENCY OF GENETIC EYE DISEASES IN A GENETIC-COUNSELING CENTER

, 1995
In this study the incidence of eye diseases of genetic origin in patients attending our genetic counseling center for a period of almost six years is documented, The frequency of retinitis pigmentosa, congenital cataracts, lens dislocation ...
ELCIOGLU, M, FUHRMANN, W, ELCIOGLU, N
core  

Bicuspid Aortic Valve: a Review with Recommendations for Genetic Counseling

, 2016
Bicuspid aortic valve (BAV) is the most common congenital heart defect and falls in the spectrum of left-sided heart defects, also known as left ventricular outflow tract obstructive (LVOTO) defects.
Stephanie M. Ware, Landis, Benjamin J., Benjamin M. Helm, Ware, Stephanie M., Freeze, Samantha L., Helm, Benjamin M., Samantha L. Freeze, Benjamin J. Landis   +7 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Issues, challenges, and future perspectives of genetic counseling in Republic of Korea: Perspectives of laboratory physicians based on a 2022 survey

The field of genetic counseling (GC) in the Republic of Korea has evolved from a single medical doctor's clinic to a multidisciplinary service with medical geneticists and non-medical professionals working as a team.
Namhee Kim, Jieun Kim, committee of Genetic Counseling in Korean Society for Genetic Diagnostics (KSGD), Soo Hyun Seo, Jungwon Huh, Jongha Yoo, Do-Hoon Kim, Sun-Young Kong, Eul Joo Seo   +8 more
core   +1 more source