Results 101 to 110 of about 27,725 (297)
Bouvard et Pécuchet et le savoir médical
This article proposes to study the medical documents gathered by Flaubert for the preparation of Chapter III of Bouvart et Pécuchet. This substantial file, which contains reading notes taken by the novelist for the writing of the medical chapter, allows ...
Norioki Sugaya
doaj +1 more source
Genetic Influences on Anxiety in Children: What we've Learned and Where we're Heading [PDF]
Anxiety is a common problem, typically beginning early in life. This article explores reasons for individual differences in levels of anxiety among children, by reviewing the genetic literature.
Eley, Thalia C., Gregory, Alice M.
core +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Genetic Algorithms and Critical Phenomena
Genetic algorithms based on natural selection and minimal fluctuations have been applied to model physical and biological systems. Critical exponents have been extracted via computational simulations of nucleation for colossal magnetoresistance, heavy ions liquid-gas phase transitions and HIV to AIDS transition.
Barrañón, A. +2 more
openaire +2 more sources
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
"Kosmos" ("Cosmos") is calling Polish genetic criticism
W pierwszej części artykułu omówiono powinowactwa światopoglądowe i tematyczne między "Kosmosem" Witolda Gombrowicza a krytyką genetyczną, czyli badaniem procesu tekstotwórczego.
Antoniuk, Mateusz
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Creative concurrence: gearing genetic criticism for the sociology of writing
: This essay is an attempt to come to terms with a phenomenon that characterizes many authors\u2019 oeuvres: the concurrent composition of several works.
Van Hulle, Dirk
core
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

