Results 101 to 110 of about 27,725 (297)

Bouvard et Pécuchet et le savoir médical

open access: yesFlaubert: Revue Critique et Génétique, 2009
This article proposes to study the medical documents gathered by Flaubert for the preparation of Chapter III of Bouvart et Pécuchet. This substantial file, which contains reading notes taken by the novelist for the writing of the medical chapter, allows ...
Norioki Sugaya
doaj   +1 more source

Genetic Influences on Anxiety in Children: What we've Learned and Where we're Heading [PDF]

open access: yes, 2007
Anxiety is a common problem, typically beginning early in life. This article explores reasons for individual differences in levels of anxiety among children, by reviewing the genetic literature.
Eley, Thalia C., Gregory, Alice M.
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Genetic Algorithms and Critical Phenomena

open access: yes, 2003
Genetic algorithms based on natural selection and minimal fluctuations have been applied to model physical and biological systems. Critical exponents have been extracted via computational simulations of nucleation for colossal magnetoresistance, heavy ions liquid-gas phase transitions and HIV to AIDS transition.
Barrañón, A.   +2 more
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

"Kosmos" ("Cosmos") is calling Polish genetic criticism

open access: yes, 2020
W pierwszej części artykułu omówiono powinowactwa światopoglądowe i tematyczne między "Kosmosem" Witolda Gombrowicza a krytyką genetyczną, czyli badaniem procesu tekstotwórczego.
Antoniuk, Mateusz
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Creative concurrence: gearing genetic criticism for the sociology of writing

open access: yes, 2021
: This essay is an attempt to come to terms with a phenomenon that characterizes many authors\u2019 oeuvres: the concurrent composition of several works.
Van Hulle, Dirk
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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