Results 111 to 120 of about 12,192,107 (344)
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Growth disorders caused by variants in epigenetic regulators: progress and prospects
Frontiers in EndocrinologyEpigenetic modifications play an important role in regulation of transcription and gene expression. The molecular machinery governing epigenetic modifications, also known as epigenetic regulators, include non-coding RNA, chromatin remodelers, and enzymes
Julian C. Lui
doaj +1 more source
Scientific Reports, 2018 We generated cattle embryos using mitochondrial supplementation and somatic cell nuclear transfer (SCNT), named miNT, to determine how additional mitochondrial DNA (mtDNA) modulates the nuclear genome.
Kanokwan Srirattana, Justin C. St. John
doaj +1 more source
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Importance of DNA Sequencing for Abnormal Hemoglobins Detected by HPLC Screening
Turkish Journal of Hematology, 2020 Duran Canatan +4 more
doaj +1 more source
From rumors to genetic isolates
Genetics and Molecular Biology, 2014 Here we propose a registration process for population genetic isolates, usually geographic clusters of genetic disorders, based on the systematic search of rumors, defined as any type of account regardless of its reliability.
Eduardo E. Castilla +1 more
doaj +1 more source
Integrated analysis of variants and pathways in genome-wide association studies using polygenic models of disease [PDF]
arXiv, 2012 Many common diseases are highly polygenic, modulated by a large number genetic factors with small effects on susceptibility to disease. These small effects are difficult to map reliably in genetic association studies. To address this problem, researchers have developed methods that aggregate information over sets of related genes, such as biological ...
arxiv
Cystinuria: biochemical evidence for three genetically distinct diseases. [PDF]
, 1966 Leah Rosenberg +3 more
openalex +1 more source
Fertility preservation for genetic diseases leading to premature ovarian insufficiency (POI)
Journal of Assisted Reproduction and Genetics, 2021 A. La Marca, E. Mastellari
semanticscholar +1 more source
Molecular Oncology, EarlyView.The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina +17 more
wiley +1 more source