Results 131 to 140 of about 11,828,008 (230)

Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal system. [PDF]

open access: yes, 2019
Vasoactive intestinal peptide (VIP), a gut peptide hormone originally reported as a vasodilator in 1970, has multiple physiological and pathological effects on development, growth, and the control of neuronal, epithelial, and endocrine cell functions ...
Akiba, Yasutada   +2 more
core  

The Future of Genetic Disease Studies: Assembling an Updated Multidisciplinary Toolbox

open access: yesFrontiers in Cell and Developmental Biology, 2022
Swetha Ramadesikan   +2 more
doaj   +1 more source

Gene-associated Disease Discovery Powered by Large Language Models [PDF]

open access: yesarXiv
The intricate relationship between genetic variation and human diseases has been a focal point of medical research, evidenced by the identification of risk genes regarding specific diseases. The advent of advanced genome sequencing techniques has significantly improved the efficiency and cost-effectiveness of detecting these genetic markers, playing a ...
arxiv  

How to develop smarter host mixtures to control plant disease? [PDF]

open access: yesarXiv, 2014
A looming challenge for agriculture is sustainable intensification of food production to feed the growing human population. Current chemical and genetic technologies used to manage plant diseases are highly vulnerable to pathogen evolution and are not sustainable.
arxiv  

Gene Therapy for Human Genetic Disease? [PDF]

open access: bronze, 1972
Elizabeth F. Neufeld, Charles C. Sweeley
openalex   +1 more source

Distinguishing correlation from causation using genome-wide association studies [PDF]

open access: yesO'Connor, Luke J. and Alkes L. Price. "Distinguishing genetic correlation from causation across 52 diseases and complex traits." Nature genetics (2018), 2018
Genome-wide association studies (GWAS) have emerged as a rich source of genetic clues into disease biology, and they have revealed strong genetic correlations among many diseases and traits. Some of these genetic correlations may reflect causal relationships.
arxiv  

Genetics-Driven Personalized Disease Progression Model [PDF]

open access: yesarXiv
Modeling disease progression through multiple stages is critical for clinical decision-making for chronic diseases, e.g., cancer, diabetes, chronic kidney diseases, and so on. Existing approaches often model the disease progression as a uniform trajectory pattern at the population level. However, chronic diseases are highly heterogeneous and often have
arxiv  

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