Results 61 to 70 of about 4,213,652 (301)
Isolation-by-distance in landscapes: considerations for landscape genetics [PDF]
Heredity, 2014 In landscape genetics, isolation-by-distance (IBD) is regarded as a baseline pattern that is obtained without additional effects of landscape elements on gene flow. However, the configuration of suitable habitat patches determines deme topology, which in turn should affect rates of gene flow.
Van Strien, M. J. +2 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Molecular Genetics & Genomic Medicine, 2023 Background The Souss, located in southern Morocco, is one of the oldest areas of human settlement in North Africa. Despite this historical relevance, the Souss has not received sufficient attention in terms of population genetic studies.
Noura Dahbi +6 more
doaj +1 more source
Genetic Distance and International Migrant Selection [PDF]
, 2015 This paper looks at the effect of the relatedness of two countries, measured by their genetic distance, on educational migrant selection. We analyze bilateral country-level education-specific migration stocks from 85 sending countries to the 15 main destination countries in 2000 and show that country pairs with larger genetic distances exhibit more ...
Tim Krieger, Laura Renner, Jens Ruhose
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Generalized Distance in Genetic Studies
Human Heredity, 1967 info:eu-repo/semantics ...
openaire +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Genetic analysis of silver-fir populations in the North Carpathian and Sudeten Mountains
Acta Societatis Botanicorum Poloniae, 2011 Seeds collected from individual trees in the 16 Carpathian and 2 Sudeten silver-fir (Abies alba) populations were studied with the starch gel electrophoresis in megagametophytes using 14 enzyme systems with 28 loci. The results show that the geographical
Leon Mejnartowicz
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Estimating genome reversal distance by genetic algorithm [PDF]
The 2003 Congress on Evolutionary Computation, 2003. CEC '03., 2004 Sorting by reversals is an important problem in inferring the evolutionary relationship between two genomes. The problem of sorting unsigned permutation has been proven to be NP-hard. The best guaranteed error bounded is the 3/2- approximation algorithm. However, the problem of sorting signed permutation can be solved easily.
Andy Auyeung, Ajith Abraham
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