Results 41 to 50 of about 638,933 (232)

Genetic diversity and genetic burden in humans

Infection, Genetics and Evolution, 2006
We discuss categories of genetic diversity in humans. Neutral diversity, population differences in frequencies of genetic markers that we think are invisible to natural selection, provides a passive record of population history but is otherwise of little interest in human biology.
Henry, Harpending, Gregory, Cochran
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Unraveling the meiotic puzzle: chromosome count, meiotic behaviour, and reproductive challenges in Phlomis cashmeriana Royle ex Benth. from the Kashmir Himalaya

Frontiers in Conservation Science
Meiotic stability is crucial for maintaining reproductive success and genetic diversity in plants, especially in montane regions like the Himalaya, where fluctuating environmental conditions can disrupt normal chromosome behavior.
Roof Ul Qadir, Hanan Javid, Aijaz Hassan Ganie, Bilal A. Wani, Irshad A. Nawchoo, Junaid A. Magray   +5 more
doaj   +1 more source

Genetic Selection and Conservation of Genetic Diversity* [PDF]

Reproduction in Domestic Animals, 2012
ContentsFor 100s of years, livestock producers have employed various types of selection to alter livestock populations. Current selection strategies are little different, except our technologies for selection have become more powerful. Genetic resources at the breed level have been in and out of favour over time.
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Untangling the reproductive puzzle: how floral traits, pollinator behavior, and breeding strategy shape reproductive success in the Himalayan medicinal herb Phytolacca acinosa Roxb

Frontiers in Plant Science
Understanding the reproductive ecology of plants is crucial for devising strategies for their sustainable utilization and effective conservation.
Junaid A. Magray, Bilal A. Wani, Irshad A. Nawchoo, Aijaz H. Ganie, Hanan Javid, Roof Ul Qadir   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Prokaryotic taxa play keystone roles in the soil microbiome associated with woody perennial plants in the genus Buxus

Ecology and Evolution, 2019
The microbiome associated with ornamental plants has largely been neglected, despite its potential for impacting plant health. This work characterized the composition, diversity, and microbial co‐associations in the soil microbiome associated with ...
Nicholas LeBlanc, Jo Anne Crouch
doaj   +1 more source

Molecular and morphological characterization of the alfalfa cyst nematode, Heterodera medicaginis, from Utah [PDF]

Journal of Nematology, 2020
Zafar A. Handoo, Andrea M. Skantar, Saad L. Hafez, Mihail R. Kantor, Maria N. Hult, Stephen A. Rogers   +5 more
doaj   +1 more source