Results 61 to 70 of about 780,483 (315)

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology

Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos, Lindsay A. Jibb, Gary Rodin   +2 more
wiley   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Cross-species optimization of nuclei isolation in ten plant species

Plant Methods
Single-cell technologies are transforming plant biology, yet broadly transferable nuclei isolation remains a key bottleneck for snRNA-seq. We developed a reproducible, cost-efficient Percoll-based workflow that is applicable to multiple maize tissues and
Yun Luo, Jiali Yan, Thuy La, Edward S. Buckler, Jianbing Yan, M. Cinta Romay   +5 more
doaj   +1 more source

Genetic progress in rice yield: preliminary insights from historically released varieties in Sub-Saharan Africa

Frontiers in Plant Science
Rice is a vital staple crop in sub-Saharan Africa (SSA), where improving grain yield is critical for food security and economic growth. Assessing genetic gain over time is essential for measuring breeding effectiveness and guiding future strategies and ...
Shailesh Yadav, Vimal Kumar Semwal, Gbènakpon Aubin Y. G. Amagnide, Esther Pegalepo, Kora Orou Kobi, Kossi Lorimpo Adjah, Nana Kofi Abaka Amoah, Raafat El-Namaky, Negussie Zenna, Epa N’da Ghislain Noumouha, Faye Omar Ndaw, Muhammad Liman Muhammad, Laho Mamadou Barry, Medoune Khouma, Dolo Menidiou, Dule Zhao, Baboucarr Manneh   +16 more
doaj   +1 more source

Development and Implementation of a Disease‐Targeted Storybook as a Clinical Tool for Children With Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin, Usanarat Anurathapan, Rawiwan Roongpraiwan, Potchanee Dandamrongrak, Siriporn Nakhonchai, Pawin Numthavaj, Vilawan Chirdkiatgumchai   +6 more
wiley   +1 more source

Genetic diversity and population structure of Ascochyta rabiei from the western Iranian Ilam and Kermanshah provinces using MAT and SSR markers [PDF]

, 2010
Knowledge of genetic diversity in A. rabiei provides different levels of information that are important in the management of crop germplasm resources. Gene flow on a regional level indicates a significant potential risk for the regional spread of novel ...
Ellwood, S.R., Oliver, Richard, Mohammad Reza Naghavi, Lichtenzveig, Judith, Okhovat, S., Javannikkhah, M., Okhovat, S.M., Ellwood, Simon, Naghavi, M.R., Judith Lichtenzveig, Javannikhah, M., Naghavi, M., Khoshnood Nourollahi, Oliver, R.P., Simon R. Ellwood, Mohammad Javannikkhah, Richard P. Oliver, Nourollahi, K., Lichtenzveig, J., Sayed Mahmmod Okhovat   +19 more
core   +2 more sources

Unraveling the meiotic puzzle: chromosome count, meiotic behaviour, and reproductive challenges in Phlomis cashmeriana Royle ex Benth. from the Kashmir Himalaya

Frontiers in Conservation Science
Meiotic stability is crucial for maintaining reproductive success and genetic diversity in plants, especially in montane regions like the Himalaya, where fluctuating environmental conditions can disrupt normal chromosome behavior.
Roof Ul Qadir, Hanan Javid, Aijaz Hassan Ganie, Bilal A. Wani, Irshad A. Nawchoo, Junaid A. Magray   +5 more
doaj   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

Genetic diversity of maize (Zea mays L. ssp. mays) in communities of the western highlands of Guatemala: geographical patterns and processes. [PDF]

, 2008
This study concerns spatial genetic patterning, seed flow and the impact of modern varieties in maize populations in Chimaltenango, Guatemala. It uses a collection of 79 maize seed samples from farmers in the area and five samples derived from modern ...
Molina, L.G., Fuentes, M.R., Etten, J., van, Ponciano, K.M.   +3 more
core   +1 more source