Results 111 to 120 of about 92,865 (288)
Royal Society Open ScienceGambusia nobilis is a federally endangered species found across a fragmented distribution within the Pecos River Drainage of Texas and New Mexico, USA.
David S. Portnoy +7 more
doaj +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Does Early Homo Dental Variation Follow a Neutral Pattern of Divergence?
PaleoAnthropologyThe fragmentary early Homo fossil record represents a temporally expansive and complex lineage that is morphologically and geographically diverse. This large amount of variation, which also captures the transition period from Australopithecus to Homo ...
Luca Del Giacco, Lauren Schroeder
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Genetic drift among native people from South American Gran Chaco region affects interleukin 1 receptor antagonist variation [PDF]
, 2015 Fil: Catanesi, Cecilia Inés. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Laboratorio de Genética Molecular; ArgentinaFil: Glesmann, Laura Angela. Universidad Nacional de La Plata.
Catanesi, Cecilia Inés +1 more
core
, 2017 Genetic drift is stochastic fluctuations of alleles frequencies in a population due to sampling effects. We consider a model of drift in an equilibrium population, with high mutation rates: few functional mutations per generation. Such mutation rates are common in multicellular organisms including humans, however they are not explicitly considered in ...
Shadrin, Alexey A. +1 more
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Genetic Drift and Anthropometric Variation in Ireland [PDF]
, 2013 The effect of genetic drift on the genetic structure of seven Irish populations was investigated using anthropometric data collected during the 1890s on 259 adult males. These populations ranged in size from 769 to 3757, were relatively stable over time,
Relethford, John H.
core
Solution of Premature Convergence and Genetic Drift Based on Population Cluster
工程科学与技术, 2006 :For solving effectively premature convergence and genetic drift that often occur in applying Gas to practice, the reason for the premature and genetic drift was analyzed.
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source