Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Artificial and Natural Genetic Information Processing [PDF]
, 2017 Conventional methods of genetic engineering and more recent genome editing techniques focus on identifying genetic target sequences for manipulation.
Witzany, Guenther
core
B.M.A. Scientific Meeting, Leicester: Symposia on Medicine and Engineering, Genetic Counselling, Parkinson's Disease, Radioisotopes, and Ultrasonics [PDF]
, 1971 openalex +1 more source
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source
Matrix genetics, part 1: permutations of positions in triplets and symmetries of genetic matrices [PDF]
arXiv, 2008 The Kronecker family of the genetic matrices is investigated, which is based on the genetic matrix [C T; A G], where C, T, A, G are the letters of the genetic alphabet. The matrix [C T; A G] in the second Kronecker power is the (4*4)-matrix of 16 duplets. The matrix [C T; A G] in the third Kronecker power is the (8*8)-matrix of 64 triplets.
arxiv
Genetic Engineering Online Lessons Improve Teaching and Increase Knowledge and Accepting Attitudes Among Students [PDF]
, 2015 Genetic engineering has been used in the production of food in the U.S. for nearly three decades, however, science literacy in genetic engineering among consumers is still low.
Troupe, Grace
core +1 more source
Human Genetic Engineering: A Survey of Student Value Stances [PDF]
, 1975 Sara McCormack Wilson +2 more
openalex +1 more source
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
What you always wanted to know about genetic algorithms but were afraid to hear [PDF]
arXiv, 2000 In spite of their seemingly "obvious" virtues as a search strategy, genetic algorithms have ended up playing only a modest role as design tools in science and engineering. We review the reasons for this apparent failure, and we suggest a more relaxed view of their utility.
arxiv
Bioethics, Complementarity, and Corporate Criminal Liability [PDF]
, 2017 This article provides a brief introduction to some contemporary challenges found in the intersection of bioethics and international criminal law involving genetic privacy, organ trafficking, genetic engineering, and cloning.
Long, Ryan
core