Results 121 to 130 of about 5,820,249 (380)
Regulating Human Gene Therapy [PDF]
, 1985 Scientific developments have moved the public debate on genetic engineering to the issue of human gene therapy. Because so many important societal values must be weighed in deciding which, if any, of the first protocols for human gene therapy should be ...
Areen, Judith C.
core +1 more source
Strategies for Genetically Engineering Hypoimmunogenic Universal Pluripotent Stem Cells [PDF]
, 2020 Wei Zhao +10 more
openalex +1 more source
Genetic engineering of T cells for immunotherapy
Nature reviews genetics, 2021 Gavin I. Ellis, N. Sheppard, J. Riley
semanticscholar +1 more source
ORBIT: a New Paradigm for Genetic Engineering of Mycobacterial Chromosomes
mBio, 2018 We sought to develop a system that could increase the usefulness of oligonucleotide-mediated recombineering of bacterial chromosomes by expanding the types of modifications generated by an oligonucleotide (i.e., insertions and deletions) and by making ...
K. Murphy +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Bacterial LuxR solos have evolved to respond to different molecules including signals from plants
Frontiers in Plant Science, 2013 A future challenge will be understanding the extensive communication that most likely takes place in bacterial interspecies and interkingdom signaling between plants and bacteria.
Hitendra K. Patel +5 more
doaj +1 more source
Genetic engineering and trade [PDF]
Advocates of the use of genetic engineering techniques in agriculture contend that this new biotechnology promises increased productivity, better use of natural resources and more nutritious foods.
Nielsen, Chantal Pohl +2 more
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Embryos as Patients? Medical Provider Duties in the Age of CRISPR/Cas9 [PDF]
, 2017 The CRISPR/Cas9 genome engineering platform is the first method of gene editing that could potentially be used to treat genetic disorders in human embryos. No past therapies, genetic or otherwise, have been intended or used to treat disorders in existent
Powell, G. Edward, III
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
A new approach to planning in vitro and in vivo experiments for cardiovascular stents. (1) Fundamentals of design procedures [PDF]
, 2000 Copyright @ 2000 Pacini Editore SpAWhile the use of cardiovascular stents is internationally widespread re-stenosis remains a common problem. There are a number of different designs, and this project seeks for design improvements leading to a reduction ...
Atherton, MA, Collins, MW, Doorly, DJ
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