Results 121 to 130 of about 723,030 (329)

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

open access: yesMolecular Oncology, EarlyView.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park   +8 more
wiley   +1 more source

DIANA, a program for Feynman Diagram Evaluation [PDF]

open access: yes, 1999
A C-program DIANA (DIagram ANAlyser) for the automatic Feynman diagram evaluation is presented.Comment: LaTeX, 5 pages, no figures; talk given at 6th International Workshop on Software Engineering, Artificial Intelligence, Neural Nets, Genetic ...
Fleischer, J., Tentyukov, M.
core   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

A genetic algorithm for finding pulse sequences for NMR quantum computing [PDF]

open access: yesParitantra - Journal of Systems Science and Engineering 20, 32-42 (2011), 2004
We present a genetic algorithm for finding a set of pulse sequences, or rotations, for a given quantum logic gate, as implemented by NMR. We demonstrate the utility of the method by showing that shorter sequences than have been previously published can be found for both a CNOT and for the central part of Shor's algorithm (for N=15.) Artificial ...
arxiv  

Developing Genetic Tools for Geobacillus [PDF]

open access: yes, 2014
Bacillus and Geobacillus are the primary bacterium used in biotechnology industries due to their ability to excrete extracellular materials such as proteins, enzymes and other byproducts.
Artale, Brittany
core   +2 more sources

Genomic landscape and preclinical models of angiosarcoma

open access: yesMolecular Oncology, EarlyView.
Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton   +3 more
wiley   +1 more source

Anhydrobiotic cells of the nematocidic agent Tsukamurella paurometabola C-924

open access: yesBiotecnología Aplicada
Biological control of nematodes is a valuable alternative to the use of chemical nematicides in agriculture, because of the high negative impact generated by such chemicals in agroecosystems.
Armando Hernández   +15 more
doaj  

Control of Complex Systems Using Bayesian Networks and Genetic Algorithm [PDF]

open access: yesarXiv, 2007
A method based on Bayesian neural networks and genetic algorithm is proposed to control the fermentation process. The relationship between input and output variables is modelled using Bayesian neural network that is trained using hybrid Monte Carlo method.
arxiv  

Procreative Beneficence and Genetic Enhancement [PDF]

open access: yes, 2018
Imagine a world where everyone is healthy, intelligent, long living and happy. Intuitively this seems wonderful albeit unrealistic. However, recent scientic breakthroughs in genetic engineering, namely CRISPR/Cas bring the question into public discourse,
Veit, Walter
core   +1 more source

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