Results 131 to 140 of about 723,030 (329)

Genetic engineering: Genentech claims factor VIII [PDF]

, 1984
Tim Beardsley
openalex   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

In memoriam

Genetics & Applications, 2019
Institute for Genetic Engineering and Biotechnology
doaj   +1 more source

Genetic engineering patents: Contest in prospect over Interferon rights [PDF]

, 1985
Tim Beardsley
openalex   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Influence of albumin content and freeze-drying on the immunogenicity of human recombinant Interferon alpha-2b in mice

Biotecnología Aplicada
Antibodies against interferon (IFN) could explain the lack of response to treatment or the development of autoimmune processes. The albumin content and the freeze-drying process of IFN alpha formulations could be involved in the generation of such ...
Idrian García, Hailen Bobillo, Yordanka Soria, Majel Cervantes, Cimara H Bermúdez, Gisou Díaz, Iraldo Bello, Angela D Tuero, Pedro A López   +8 more
doaj  

Futurenatural? A future of science through the lens of wisdom [PDF]

, 1999
This is a PDF version of an article published in Heythrop Journal© 1999. The definitive version is available at www.blackwell-synergy.com.This article discusses genetic engineering and Christian theories of wisdom, particularly in relation in creation ...
Deane-Drummond, Celia
core  

Biotechnology: Genetic engineering minus glamour [PDF]

, 1986
Karen Wright
openalex   +1 more source

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

Molecular Oncology, EarlyView.
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso, Shivani Bailey, Luz Alonso‐Crisostomo, Dawn Ward, Christos Panayi, Zachary G. L. Scurlock, Harpreet K. Saini, Stephen P. Smith, James C. Nicholson, Anton J. Enright, Cinzia G. Scarpini, Nicholas Coleman, Matthew J. Murray   +12 more
wiley   +1 more source

Genetic Engineering of Plants – An Agricultural Perspective. Edited by T. Kosuge, C. P. Meredith and A. Hollaender. Plenum Press, 233 Spring Street, New York, N.Y. (1983). $69.50. ISBN 0 306 41353 1. [PDF]

, 1983
Steven M. Smith
openalex   +1 more source