Results 131 to 140 of about 5,820,249 (380)

Genetic Engineering of Energy Crops to Reduce Recalcitrance and Enhance Biomass Digestibility [PDF]

, 2018
Monika Yadav, Kunwar Paritosh, Aakash Chawade, Nidhi Pareek, Vivekanand Vivekanand   +4 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Plasticity of the HEK-293 cells, related to the culture media, as platform to produce a subunit vaccine against classical swine fever virus

AMB Express, 2019
Classical swine fever (CSF) is a contagious disease that causes a high mortality to domestic and wild pigs. Its causative agent is an enveloped Pestivirus named Classical Swine Fever Virus (CSFV).
Elianet Lorenzo, Lidice Méndez, Elsa Rodríguez, Nemecio Gonzalez, Gleysin Cabrera, Carlos Pérez, Rafael Pimentel, Yusmel Sordo, Maria P. Molto, Talia Sardina, Alina Rodríguez-Mallon, Mario P. Estrada   +11 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Feature engineering through two-level genetic algorithm

Machine Learning with Applications
Deep learning models are widely used for their high predictive performance, but often lack interpretability. Traditional machine learning methods, such as logistic regression and ensemble models, offer greater interpretability but typically have lower ...
Aditi Gulati, Armin Felahatpisheh, Camilo E. Valderrama   +2 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Defining the Agricultural Biotechnology Policy of the Philippines [PDF]

Agricultural biotechnology offers a whole new range of possibilities to solving the problems that impinge on the productivity of the agriculture sector and its ability to feed the growing human population.
Halos, Saturnina C.
core  

Genetic engineering of pharmacologically regulated T cells, specific for breast cancer target antigens [PDF]

, 2010
Scott Wilkie, S. Burbridge, D.H. Davies, Laura Chiapero-Stanke, Julie Foster, SJ Mather, John Maher   +6 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Genetic Insights Into Type 2 Diabetes Mellitus Susceptibility: A Case-Control Study of the ADIPOQ rs1501299 Polymorphism in the Population of Noakhali Region of Bangladesh

Genetics Research
Type 2 diabetes mellitus (T2DM) is a global health concern, particularly prevalent in low to middle-income countries like Bangladesh. This case-control study aims to explore the correlation between the ADIPOQ rs1501299 polymorphism and susceptibility to ...
Md. Anamul Haque, Md. Sad Salabi Sawrav, Shipan Das Gupta, Shuvo Chandra Das, Dhirendra Nath Barman, Mohammed Mafizul Islam, Md. Murad Hossain   +6 more
doaj   +1 more source