Results 151 to 160 of about 6,955,736 (304)

Seeking perfection: a Kantian look at human genetic engineering

open access: yes, 2007
It is tempting to argue that Kantian moral philosophy justifies prohibiting both human germ-line genetic engineering and non-therapeutic genetic engineering because they fail to respect human dignity.
Gunderson, Martin
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Engineering Vanderbilt; Vol. 44 No. 02, 2003

open access: yes, 2003
Engineering Vanderbilt (formerly Engineering News) is the newsletter of the Vanderbilt University School of Engineering.School of ...
Vanderbilt University. School of Engineering
core  

God players: Genetic engineering

open access: yesContemporary Clinical Dentistry, 2010
S G Damle
doaj  

Soybean genetic engineering in Brazil and South America - A review. [PDF]

open access: yesGenet Mol Biol
Fuganti-Pagliarini R   +8 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Engineering Vanderbilt; Vol. 47 No. 01, 2006

open access: yes, 2006
Engineering Vanderbilt (formerly Engineering News) is the newsletter of the Vanderbilt University School of EngineeringSchool of ...
Vanderbilt University. School of Engineering
core  

Genetic engineering of <i>Staphylococcus haemolyticus</i>: overcoming restriction-modification barriers and targeting virulence genes. [PDF]

open access: yesMicrob Genom
Venter HJ   +7 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Engineering Vanderbilt; Vol. 50 No. 01, 2009

open access: yes, 2009
Engineering Vanderbilt (formerly Engineering News) is the newsletter of the Vanderbilt University School of Engineering.Vanderbilt University.
Vanderbilt University. School of Engineering
core  

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