Results 231 to 240 of about 6,955,736 (304)

GENETIC ENGINEERING: PRINCIPLES AND METHODS, VOLUME 4

, 1982

core  

Unlocking the Potential for Genetic Engineering of the Straw-Degrading Mushroom <i>Stropharia rugosoannulata</i> by Constructing a CRISPR/Cas9 Gene Editing System. [PDF]

J Fungi (Basel)
Hao H, Song S, Wang Q, Tong Z, Xu W, Yang J, Yue Y, Xiao T, Zhang Y, Zhang J, Chen H.   +10 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

GENETIC ENGINEERING: PRINCIPLES AND METHODS, VOLUME 5

, 1983

core  

Genetic engineering to improve resistance against heavy metal stress in <i>Synechocystis</i> sp. PCC 6803. [PDF]

Appl Environ Microbiol
Yang Y, Zheng C, Gao L, Jiang X, Xu J, Zhang W, Peng Y, Han J, Sun M, Ma W, Shi W, Shen X.   +11 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Genetic engineering in diatoms: advances and prospects. [PDF]

Plant J
Li Y, Deng L, Walker EJL, Karas BJ, Mock T.   +4 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A Synergistic Genetic Engineering Strategy Induced Nervonic Acid in <i>Brassica juncea</i> and <i>Brassica napus</i>. [PDF]

Int J Mol Sci
Wang P, Liu X, Xiong X, Wu G, Liu F.
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source