Results 71 to 80 of about 1,119,255 (298)
Plant Genetic Resources: Selected Issues from Genetic Erosion to Genetic Engineering
Journal of Agriculture and Rural Development in the Tropics and Subtropics, 2008 Plant Genetic Resources (PGR) continue to play an important role in the development of agriculture. The following aspects receive a special consideration:1. Definition. The term was coined in 1970.
Karl Hammer, Yifru Teklu
doaj
Use of Molecular Genetic Engineering in the Study of Animal Parasites and Their Vectors [PDF]
, 1989 Molecular genetics coupled with advances in immunology and parasite culture has become a powerful tool to study animal parasites and their vectors. Recombinant DNA techniques allow one to identify individual genes of DNA probes, amplify the nucleic acid ...
LoVerde, P. T. (Philip)
core
Robust optimization of cardiovascular stents: A comparison of methods [PDF]
, 2004 This is the post-print version of the Article. The official published version can be accssed from the links below. Copyright @ 2004 Taylor & FrancisModern engineering design contains both creative and analytic components.
Atherton, MA, Bates, RA
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Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Human Vaccines & Immunotherapeutics, 2017 The protein composition of an Outer Membrane Vesicle (OMV) preparation that constitutes the active pharmaceutical ingredient of VA-MENGOC-BC®, an effective vaccine against Neisseria meningitidis serogroups B, and C is presented.
Yordanka Masforrol +11 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Genetic algorithms with memory- and elitism-based immigrants in dynamic environments [PDF]
, 2008 Copyright @ 2008 by the Massachusetts Institute of TechnologyIn recent years the genetic algorithm community has shown a growing interest in studying dynamic optimization problems. Several approaches have been devised.
Shengxiang Yang, Trojanowski K.
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Reverse engineering of genetic networks with Bayesian networks [PDF]
, 2003 This paper provides a brief introduction to learning Bayesian networks from gene-expression data. The method is contrasted with other approaches to the reverse engineering of biochemical networks, and the Bayesian learning paradigm is briefly described ...
Husmeier, D.
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