Results 51 to 60 of about 469,914 (305)
An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene
International Journal of Genomics, 2023 Mesenchymal–epithelial transition (MET) factor is a proto-oncogene encoding tyrosine kinase receptor with hepatocyte growth factor (HGF) or scatter factor (SF). It is found on the human chromosome number 7 and regulates the diverse cellular mechanisms of
Fayeza Sadia Laskar +6 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Photothermal Genetic Engineering [PDF]
ACS Nano, 2012 Optical methods for manipulation of cellular function have enabled deconstruction of genetic and neural circuits in vitro and in vivo. Plasmonic gold nanomaterials provide an alternative platform for external optical manipulation of genetic circuits.
Deisseroth, Karl +1 more
openaire +4 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Genetic Engineering, Part 2: How Genes Are Engineered [PDF]
, 2008 Answers questions as it introduces the process of genetic ...
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Social acceptance of genetic engineering technology
PLoS ONE, 2023 Genetic engineering of animals has been proposed to address societal problems, but public acceptance of the use of this technology is unclear. Previous work has shown that the source of information proposing the technology (e.g. companies, universities),
Katherine E. Koralesky +5 more
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2006 List of illustrations -- Acknowledgments -- Preface -- 1. "It's alive!" public perceptions of genetic engineering -- 2. History of genetic engineering from Mendel to (genome) maps -- 3.
Herring, Mark Y.
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Applications of genetic engineering to agriculture [PDF]
, 1985 This book was first published in 1985. For those working in molecular biology, this book describes techniques in plant genetic research and the practical application of genetic engineering to important crop plants such as the potato. The various chapters
Jones, M.G.K., Jones, M. G. K.
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