Results 51 to 60 of about 6,955,736 (304)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Genetic engineering: part 1 [Frontiers of biomedical engineering]

open access: yes, 2011
Educação Superior::Engenharias::Engenharia BiomédicaPresents a course with the professor of Chemical and Biomedical Engineering at Yale University, W. Mark Saltzman about Frontiers of Biomedical Engineering.
Saltzman, W. Mark
core   +2 more sources

Social acceptance of genetic engineering technology

open access: yesPLoS ONE, 2023
Genetic engineering of animals has been proposed to address societal problems, but public acceptance of the use of this technology is unclear. Previous work has shown that the source of information proposing the technology (e.g. companies, universities),
Katherine E. Koralesky   +5 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A survey of genetic improvement search spaces [PDF]

open access: yes, 2019
Genetic Improvement (GI) uses automated search to improve existing software. Most GI work has focused on empirical studies that successfully apply GI to improve software's running time, fix bugs, add new features, etc. There has been little research into
Alexander, B   +17 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Plant Genetic Resources: Selected Issues from Genetic Erosion to Genetic Engineering

open access: yesJournal of Agriculture and Rural Development in the Tropics and Subtropics, 2008
Plant Genetic Resources (PGR) continue to play an important role in the development of agriculture. The following aspects receive a special consideration:1. Definition. The term was coined in 1970.
Karl Hammer, Yifru Teklu
doaj  

"Genetically engineered" nanoelectronics [PDF]

open access: yesProceedings of the First NASA/DoD Workshop on Evolvable Hardware, 2003
The quantum mechanical functionality of nanoelectronic devices such as resonant tunneling diodes (RTDs), quantum well infrared photodetectors (QWIPs), quantum well lasers, and heterostructure field effect transistors (HFETs) is enabled by material variations on an atomic scale.
Gerhard Klimeck   +3 more
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

GENETIC ENGINEERING

open access: yes, 2006
List of illustrations -- Acknowledgments -- Preface -- 1. "It's alive!" public perceptions of genetic engineering -- 2. History of genetic engineering from Mendel to (genome) maps -- 3.
Herring, Mark Y.
core   +1 more source

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