Results 31 to 40 of about 449,556 (261)
Dalla creazione alla programmazione. Il concetto di vita nell’era della biologia sintetica [PDF]
S&F_scienzaefilosofia.it, 2014 This paper aims to organize a reflection about the recent developing field of synthetic biology. It is structured into three main parts. The first one tries to point out the features of this emerging field (the analogies and the differences with the ...
Luca Lo Sapio
doaj
In-Silico Exploration of Plant Metabolites as Potential Remedies of Norovirus
Advances in Virology, 2022 Research is still being carried out to develop specific medications or vaccinations to fight norovirus, a key contributor to foodborne illness. This study evaluated certain plant-based active chemicals as prospective candidates for such treatments using ...
Zenifer Alam +6 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Human Vaccines & Immunotherapeutics, 2017 The protein composition of an Outer Membrane Vesicle (OMV) preparation that constitutes the active pharmaceutical ingredient of VA-MENGOC-BC®, an effective vaccine against Neisseria meningitidis serogroups B, and C is presented.
Yordanka Masforrol +11 more
doaj +1 more source
Historical and technological development of genetic engineering in Croatia
Studia Lexicographica, 2020 The paper provides an overview of concepts and knowledge about genetic engineering and its development in Croatia and abroad from the second half of the 20th century to the present day.
Vlatka Godinić Mikulčić
doaj +1 more source
An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene
International Journal of Genomics, 2023 Mesenchymal–epithelial transition (MET) factor is a proto-oncogene encoding tyrosine kinase receptor with hepatocyte growth factor (HGF) or scatter factor (SF). It is found on the human chromosome number 7 and regulates the diverse cellular mechanisms of
Fayeza Sadia Laskar +6 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
California agriculture and genetic engineering
California Agriculture, 1982 California Agriculture - All ...
L Lewis
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source