Results 31 to 40 of about 469,914 (305)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Prospects of genetic engineering for robust insect resistance [PDF]

open access: yes, 2014
Secondary plant metabolites are potentially of great value for providing robust resistance in plants against insect pests. Such metabolites often comprise small lipophilic molecules (SLMs), and can be similar also in terms of activity to currently used ...
Birkett, M. A.   +4 more
core   +1 more source

GENETIC ENGINEERING: PROSPECTS AND RECOMMENDATIONS

open access: yesZygon, 1984
. At the 1983 Summer Conference on the Institute on Religion in an Age of Science, working groups chaired by the coauthors outlined some of the prospects for the use of somatic and germ line genetic engineering and related biological technologies to ...
doaj   +2 more sources

Cloning of anti-HBsAg single-chain variable fragments from hybridoma cells for one-step ELISA

open access: yesBiotechnology & Biotechnological Equipment, 2017
Hepatitis B virus (HBV) infection is a worldwide health problem. More than 400 million people are chronic HBV carriers in the world. Infected individuals are at a high risk of developing liver cirrhosis and hepatocellular carcinoma as the main ...
Berrin Erdag   +7 more
doaj   +1 more source

Investigating Antimicrobial Resistance and ESBL Producing Gene in Klebsiella Isolates among Neonates and Adolescents in Southern Bangladesh

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2022
Background. Multidrug-resistant (MDR) clones of Klebsiella pneumoniae (Kpn) have been increasingly documented in community-acquired and nosocomial infections all around the globe.
Afroza Akter Tanni   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Genetic Engineering -Tool for Mankind [PDF]

open access: yes, 2018
This study was conveyed to send a driven research of Genetic Engineering its Tools, Applications, as well as Ethics which are some of the areas of Genetic Engineering which has impact on human life.
Shashwat Mandal, Christian Bach
core   +1 more source

Dalla creazione alla programmazione. Il concetto di vita nell’era della biologia sintetica [PDF]

open access: yesS&F_scienzaefilosofia.it, 2014
This paper aims to organize a reflection about the recent developing field of synthetic biology. It is structured into three main parts. The first one tries to point out the features of this emerging field (the analogies and the differences with the ...
Luca Lo Sapio
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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