Results 41 to 50 of about 6,955,736 (304)

California agriculture and genetic engineering

open access: yesCalifornia Agriculture, 1982
California Agriculture - All ...
L Lewis
doaj  

Genetic engineering in athletes [PDF]

open access: yesBMJ, 2008
Athletes who want to maximise their performance are continually tempted to use illegal drugs to gain competitive advantage and to aid recovery from training and injuries. Recent revelations of widespread doping arising from investigations of the distributionof the anabolic steroid tetrahydrogestrinone by the American company BALCO (Bay Area Laboratory ...
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Engineering Switches, Genetically [PDF]

open access: yesChemistry & Biology, 2004
Ostermeier, Guntas, and Mitchel describe a new approach to design enzymes that are allosterically regulated by an unrelated ligand . The resulting protein, constructed by nonhomologous recombination and genetic screens, displays switch-like behavior.
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Genetic engineering of salinity-tolerant plants

open access: yesCalifornia Agriculture, 1984
Not available – first paragraph follows: Molecular techniques such as recombinant DNA technology may ultimately have their most significant effect on agriculture. Recent advances raise the possibility of the development of new plant germplasm through the
R Valentine
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Genetic engineering: part 1 [Frontiers of biomedical engineering]

open access: yes, 2016
Educação Superior::Engenharias::Engenharia BiomédicaPresents a course with the professor of Chemical and Biomedical Engineering at Yale University, W. Mark Saltzman about Frontiers of Biomedical Engineering.
Saltzman, W. Mark
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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