Ethical Challenges of Germline Genetic Enhancement. [PDF]
Front Genet, 2019 The new reproductive technologies have opened the door to different processes of germline genetic enhancement by which the characteristics of an individual according to the interests of the agents involved could be selected during its gestation. Although the initiative is apparently oriented towards developing individuals that would excel in society ...
Macpherson I, Roqué MV, Segarra I.
europepmc +8 more sources
Disease Resistance and the Definition of Genetic Enhancement. [PDF]
Front Genet, 2017 Recent gene editing experiments carried out in human embryos have raised the question of whether interventions like the introduction of a CCR5-Δ32 deletion, which could provide heritable resistance to HIV infection, ought to be considered enhancements.
So D, Kleiderman E, Touré SB, Joly Y.
europepmc +6 more sources
Genetic enhancement: an avenue to combat aging-related diseases. [PDF]
Life Med, 2022 Aging is a major risk factor for multiple diseases, including cardiovascular diseases, neurodegenerative disorders, osteoarthritis, and cancer. It is accompanied by the dysregulation of stem cells and other differentiated cells, and the impairment of ...
Cai Y +6 more
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Postnatal Human Genetic Enhancement – A Consideration of Children’s Right to Be Genetically Enhanced [PDF]
Frontiers in Sociology, 2016 This paper considers children’s rights with respect to genetic enhancement (GE). It is focused on the futuristic prospect of postnatal GE, namely, genetic modifications, in vivo, of actual existing individuals. More specifically, the paper examines whether, in a future reality where pre- and postnatal human GE is safely and prevalently practiced, a ...
Sivan Tamir
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Genetic enhancement of lodging resistance in rice due to the key cell wall polymer lignin, which affects stem characteristics. [PDF]
Breed Sci, 2018 Lodging in crops seriously restricts plant growth and grain production. The genetic modification of cell walls to enhance plant mechanical strength has been suggested as a promising approach toward improving lodging resistance.
Liu S +5 more
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Ethical Concerns About Human Genetic Enhancement in the Malay Science Fiction Novels. [PDF]
Sci Eng Ethics, 2018 Advancements in science and technology have not only brought hope to humankind to produce disease-free offspring, but also offer possibilities to genetically enhance the next generation’s traits and capacities.
Isa NM, Hj Safian Shuri MF.
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Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin. [PDF]
Sci Rep, 2018 Increasing evidence supports a close relationship between Ras-ERK1/2 activation in the striatum and L-DOPA-induced dyskinesia (LID). ERK1/2 activation by L-DOPA takes place through the crosstalk between D1R/AC/PKA/DARPP-32 pathway and NMDA/Ras pathway ...
Ruiz-DeDiego I +7 more
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Procreative Beneficence and Genetic Enhancement
KRITERION – Journal of Philosophy, 2018 Abstract Imagine a world where everyone is healthy, intelligent, long living and happy. Intuitively this seems wonderful albeit unrealistic. However, recent scientific breakthroughs in genetic engineering, namely CRISPR/Cas bring the question into public discourse, how the genetic enhancement of humans should be evaluated morally.
Walter Friedrich Veit
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Genetic therapies, human genetic enhancement, and … eugenics? [PDF]
Gene Therapy, 2019 T. Friedmann
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Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding. [PDF]
Cell Res, 2017 Yang J +12 more
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