Results 91 to 100 of about 259,867 (296)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Silage maize as a potent candidate for sustainable animal husbandry development-perspectives and strategies for genetic enhancement. [PDF]

Front Genet, 2023
Karnatam KS, Mythri B, Un Nisa W, Sharma H, Meena TK, Rana P, Vikal Y, Gowda M, Dhillon BS, Sandhu S.   +9 more
europepmc   +1 more source

Long Non-Coding RNA Analysis of Vitrified Porcine Immature Oocytes During Maturation and Early Parthenogenetic Embryo Development

Cells
The preservation of porcine oocytes is critically important for advancing superior breeds and conserving genetic resources in pig production. Vitrification has gained traction as a preferred alternative to slow freezing for porcine oocytes because of its
De-Cai Xiang, Zhen He, Shi-Qi Pu, De-Meng Mu, Jing Fu, Wen-Juan Chen, Jun-Yu Jiang, Xue-Mei Li, Bao-Yu Jia, Guo-Quan Wu   +9 more
doaj   +1 more source

Robust genetic codes enhance protein evolvability

PLOS Biology
The standard genetic code defines the rules of translation for nearly every life form on Earth. It also determines the amino acid changes accessible via single-nucleotide mutations, thus influencing protein evolvability—the ability of mutation to bring forth adaptive variation in protein function.
Hana Rozhoňová, Carlos Martí-Gómez, David M. McCandlish, Joshua L. Payne   +3 more
openaire   +5 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Rice biofortification: breeding and genomic approaches for genetic enhancement of grain zinc and iron contents. [PDF]

Front Plant Sci, 2023
Senguttuvel P, G P, C J, D SR, Cn N, V J, P B, R G, J AK, Sv SP, Lv SR, As H, K S, D S, Rm S, Govindaraj M.   +15 more
europepmc   +1 more source

Identification of Novel Germplasm and Genetic Loci for Enhancing Mineral Element Uptake in Soybean

, 2023
Suhas Shinde, Anuradha Dhingra, Leonidas D’Agastino, Harshraj Shinde, Ashish B. Rajurkar, Humira Sonah, Tri D. Vuong, Matthew G. Siebecker, C. Nathan Hancock, Henry T. Nguyen, Rupesh Deshmukh, Gunvant Patil   +11 more
openalex   +1 more source

Laser capture microdissection transcriptome (LCM RNA-seq) reveals BcDFR is a key gene in anthocyanin synthesis of non-heading Chinese cabbage

BMC Genomics
Background Purple non-heading Chinese cabbage [Brassica campestris (syn. Brassica rapa) ssp. chinensis] has become popular because of its richness in anthocyanin. However, anthocyanin only accumulates in the upper epidermis of leaves. Further studies are
Qian Zhou, Xinfeng Xu, Mengjie Li, Xiaoxue Yang, Meiyun Wang, Ying Li, Xilin Hou, Tongkun Liu   +7 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Genetic enhancement, TED talks and the sense of wonder. [PDF]

Med Humanit, 2021
Filip L.
europepmc   +1 more source