Results 101 to 110 of about 259,867 (296)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Genetic enhancement of Trichoderma asperellum biocontrol potentials and carbendazim tolerance for chickpea dry root rot disease management. [PDF]

PLoS One, 2023
G R, Naik MK, Nitnavare RB, Yeshvekar R, Bhattacharya J, Bhatnagar-Mathur P, Sharma M.   +6 more
europepmc   +1 more source

Genetic Engineering and Genome Editing Advances to Enhance Floral Attributes in Ornamental Plants: An Update [PDF]

, 2023
Manjulatha Mekapogu, Hyun-Young Song, So-Hyeon Lim, Jae‐A Jung   +3 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Telomere-to-telomere genome assembly of sorghum

Scientific Data
“Cuohu Bazi” (CHBZ) is an ancient sorghum variety collected from the fields of China, known for its agronomic traits like dwarf stature, early maturation. In this study, we present the first telomere-to-telomere (T2T) and gap-free genome assembly of CHBZ
Meng Li, Chunhai Chen, Haigang Wang, Huibin Qin, Sen Hou, Xukui Yang, Jianbo Jian, Peng Gao, Minxuan Liu, Zhixin Mu   +9 more
doaj   +1 more source

Genome-Wide Identification and Characterization of TaCRY Gene Family and Its Expression in Seed Aging Process of Wheat

Current Issues in Molecular Biology
Cryptochromes (CRYs), as essential blue-light photoreceptors, play pivotal roles in modulating plant growth, development, and stress responses. Although CRY-mediated light signaling has been extensively studied in model species, their functions remain ...
Guoqing Cui, Xiuyan Cui, Junjie Wang, Menglin Lei, Xia Liu, Yanzhen Wang, Haigang Wang, Longlong Liu, Zhixin Mu, Xia Xin   +9 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Accelerated Genetic Gains in Early-Maturing Maize Hybrids following Three Periods of Genetic Enhancement for Grain Yield under Low and High Soil-Nitrogen Environments. [PDF]

Plants (Basel), 2022
Badu-Apraku B, Fakorede MAB, Abubakar AM.   +2 more
europepmc   +1 more source

Douro Vineyards: A Perspective for the Valorization and Conservation of Grapevine Genetic Resources

Agronomy
The wine industry is one of the most important industries globally, particularly for Portugal, making a significant contribution to the Portuguese Bioeconomy.
Beatriz Sousa, Susana de Sousa Araújo, Hélia Sales, Rita Pontes, João Nunes   +4 more
doaj   +1 more source