Results 51 to 60 of about 240,164 (313)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Reproduction response of Colletotrichum fungi under the fungicide stress reveals new aspects of chemical control of fungal diseases

Microbial Biotechnology, 2022
Summary Systemic fungicides and antifungals are used as frontline treatments for fungal diseases in plants and humans. It is generally accepted that fungicides will bring significant negative side‐effects to the environment and result in fungicide ...
Yong‐chao Han, Xiang‐guo Zeng, Cong Guo, Qing‐hua Zhang, Feng‐ying Chen, Li Ren, Wei‐dong Chen, Li Qin   +7 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Physiological and transcriptomic comparisons shed light on the cold stress response mechanisms of Dendrobium spp

BMC Plant Biology
Background Dendrobium spp. comprise a group of tropical orchids with ornamental and medicinal value. Dendrobium spp. are sensitive to low temperature, and the underlying cold response regulatory mechanisms in this group are unclear.
Zhiyuan Li, Shunjiao Lu, Shuangshuang Yi, Shunjin Mo, Xiaoyun Yu, Junmei Yin, Changqing Zhang   +6 more
doaj   +1 more source

Genetic testing for enhanced S-cone syndrome

The EuroBiotech Journal, 2017
Abstract We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for enhanced S-cone syndrome (ESCS). The disease has autosomal recessive inheritance, a prevalence of less than one per million, and is caused by mutations in the NR2E3 gene.
Matteo Bertelli, Munis Dundar, Tommaso Beccari, Fabiana D'Esposito, Fabiana D'Esposito, Andi Abeshi, Carla Marinelli   +6 more
openaire   +4 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

QTL Identification of the Insensitive Response to Photoperiod and Temperature in Soybean by Association Mapping

Journal of Integrative Agriculture, 2013
The insensitive response to photoperiod and temperature is an important quantitative trait for soybean in wide adaptation breeding. The natural variation in response to photoperiod and temperature was detected using 275 accessions of soybean [Glycine max
Qiao-mei ZUO, Zi-xiang WEN, Shu-yun ZHANG, Jin-feng HOU, Jun-yi GAI, De-yue YU, Han XING   +6 more
doaj  

Development and Characterization of EST-SSR Markers in the Chinese Medicinal Plant Callerya speciosa (Fabaceae)

Applications in Plant Sciences, 2013
Premise of the study: The first microsatellite primers were developed for Callerya speciosa, an important traditional medicinal plant with island-mainland distributions in China, to further investigate its genetic variability and population structure.
Li Li, Zhiying Li, Kelie Li, Bilan Huang, Li Xu   +4 more
doaj   +1 more source

Genetic Tools for the Enhancement of Probiotic Properties

Microbiology Spectrum, 2017
ABSTRACT The Lactobacillus genus is a diverse group of microorganisms, many of which are of industrial and medical relevance. Several Lactobacillus species have been used as probiotics, organisms that when present in sufficient quantities confer a health benefit to the host.
Laura Ortiz-Velez, Robert A. Britton
openaire   +2 more sources

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source